Method for Detection and Quantification of Non-Invasive Skin Sympathetic Nerve Activity

Chun Liu, Johnson Wong, Anisiia Doytchinova, Peng-Sheng Chen, Shien-Fong Lin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Sympathetic nerve activity is an important trigger of cardiac arrhythmia. Our laboratory recently developed a new method for non-invasive recording of the skin sympathetic nerve activity (SKNA) using conventional electrocardiography (ECG) patch electrodes. Recent studies showed that SKNA can adequately estimate sympathetic tone in humans. In order to improve the analysis of SKNA, we developed automatic standard assessment system based on the concept of microneurography and applied to non-invasive SKNA recording via 4 steps of signal processing. Every parameters in procedures can be manually selected by users in order to meet requirements. After using these signal processing, the results obtained by this system show improved nerve burst morphology and trend. Intuitive nerve discharge pattern and occurrence frequency can be automatically generated. Verification of the method with the cold water pressor test data further established the reliability and usefulness of the system. This new method offered a convenient tool to evaluate SKNA for comprehensive and detailed application in neurocardiology. The analysis system may facilitate the study between SKNA and cardiac arrhythmia, thus advance the field of neurocardiology research.

Original languageEnglish (US)
Title of host publication2018 International Conference on System Science and Engineering, ICSSE 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781538662854
DOIs
StatePublished - Nov 1 2018
Event2018 International Conference on System Science and Engineering, ICSSE 2018 - New Taipei City, Taiwan, Province of China
Duration: Jun 28 2018Jun 30 2018

Other

Other2018 International Conference on System Science and Engineering, ICSSE 2018
CountryTaiwan, Province of China
CityNew Taipei City
Period6/28/186/30/18

Keywords

  • Cold water pressor test
  • Microneurography
  • Nerve assessment system
  • Skin Sympathetic Nerve Activity

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Control and Optimization

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    Liu, C., Wong, J., Doytchinova, A., Chen, P-S., & Lin, S-F. (2018). Method for Detection and Quantification of Non-Invasive Skin Sympathetic Nerve Activity. In 2018 International Conference on System Science and Engineering, ICSSE 2018 [8520024] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICSSE.2018.8520024