Method of post-shock synchronized pacing in the excitable gaps

Liang Tang, Gyo Seung Hwang, Lin Yang, Shien-Fong Lin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Ventricular fibrillation (VF) can be synchronized with a novel synchronized pacing technique (SyncP) using low-energy pacing pulses, which causes pace termination of VF. Synchronized pacing (SyncP) is defined as optical recording guided real-time detection and stimulation of spatiotemporal excitable gaps. In this paper, we investigate the effect of post-shock SyncP strategy on improvement of defibrillation efficacy. After a near-threshold defibrillation shock, when the reference site detected the earliest activation of the reinitiated VF, a 5-mA electric stimulus was delivered from the post-shock pacing electrode to depolarize the excitable gap. This area of wavefront synchronization may lead to a change in the timing of VF propagation, which is important for VF termination. Here, we implemented the concept of post-shock synchronized pacing by a real-time feedback mechanism and demonstrated a successful VF termination by the post-shock SyncP strategy. Further optimization of this technique may prove effective in improving the defibrillation efficacy for low-energy ventricular defibrillation.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages4362-4365
Number of pages4
DOIs
StatePublished - 2006
Externally publishedYes
Event28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY, United States
Duration: Aug 30 2006Sep 3 2006

Other

Other28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
CountryUnited States
CityNew York, NY
Period8/30/069/3/06

Fingerprint

Optical recording
Wavefronts
Synchronization
Chemical activation
Feedback
Electrodes

ASJC Scopus subject areas

  • Bioengineering

Cite this

Tang, L., Hwang, G. S., Yang, L., & Lin, S-F. (2006). Method of post-shock synchronized pacing in the excitable gaps. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (pp. 4362-4365). [4029552] https://doi.org/10.1109/IEMBS.2006.260036

Method of post-shock synchronized pacing in the excitable gaps. / Tang, Liang; Hwang, Gyo Seung; Yang, Lin; Lin, Shien-Fong.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. p. 4362-4365 4029552.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tang, L, Hwang, GS, Yang, L & Lin, S-F 2006, Method of post-shock synchronized pacing in the excitable gaps. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings., 4029552, pp. 4362-4365, 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06, New York, NY, United States, 8/30/06. https://doi.org/10.1109/IEMBS.2006.260036
Tang L, Hwang GS, Yang L, Lin S-F. Method of post-shock synchronized pacing in the excitable gaps. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. p. 4362-4365. 4029552 https://doi.org/10.1109/IEMBS.2006.260036
Tang, Liang ; Hwang, Gyo Seung ; Yang, Lin ; Lin, Shien-Fong. / Method of post-shock synchronized pacing in the excitable gaps. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. pp. 4362-4365
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