Method of post-shock synchronized pacing in the excitable gaps

Liang Tang, Gyo Seung Hwang, Lin Yang, Shien Fong Lin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Ventricular fibrillation (VF) can be synchronized with a novel synchronized pacing technique (SyncP) using low-energy pacing pulses, which causes pace termination of VF. Synchronized pacing (SyncP) is defined as optical recording guided real-time detection and stimulation of spatiotemporal excitable gaps. In this paper, we investigate the effect of post-shock SyncP strategy on improvement of defibrillation efficacy. After a near-threshold defibrillation shock, when the reference site detected the earliest activation of the reinitiated VF, a 5-mA electric stimulus was delivered from the post-shock pacing electrode to depolarize the excitable gap. This area of wavefront synchronization may lead to a change in the timing of VF propagation, which is important for VF termination. Here, we implemented the concept of post-shock synchronized pacing by a real-time feedback mechanism and demonstrated a successful VF termination by the post-shock SyncP strategy. Further optimization of this technique may prove effective in improving the defibrillation efficacy for low-energy ventricular defibrillation.

Original languageEnglish (US)
Title of host publication28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
Pages4362-4365
Number of pages4
DOIs
StatePublished - 2006
Event28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY, United States
Duration: Aug 30 2006Sep 3 2006

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN (Print)0589-1019

Other

Other28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
CountryUnited States
CityNew York, NY
Period8/30/069/3/06

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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  • Cite this

    Tang, L., Hwang, G. S., Yang, L., & Lin, S. F. (2006). Method of post-shock synchronized pacing in the excitable gaps. In 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 (pp. 4362-4365). [4029552] (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings). https://doi.org/10.1109/IEMBS.2006.260036