Microcephaly with sacral agenesis and associated defects has rarely been reported. Presented here are 2 unrelated microcephalic infants having agenesis of the lower spine, foot deformities, urologic anomalies, and various other defects. Both family histories were essentially uninformative, but 2 second cousins of Case 1 had clubfoot. Karyotypes were normal for both patients. Each mother received hormone treatment early in her pregnancy.
|Original language||English (US)|
|Number of pages||2|
|Journal||Birth Defects: Original Article Series|
|Issue number||6 B|
|State||Published - Jan 1 1978|
ASJC Scopus subject areas
- Developmental Biology