Mild cognitive impairment: Conceptual issues and structural and functional brain correlates

Andrew J. Saykin, Heather A. Wishart

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Mild cognitive impairment (MCI) is a prevalent condition among older adults that carries a high risk of progression to Alzheimer's disease or other dementias. Given the potential for delaying or preventing the onset of dementia, efforts aimed at early detection and early intervention are important. The current paper reviews the conceptualization and diagnosis of MCI, assessment of memory complaints and deficits in the elderly, as well as recent research on the neurobiological basis of the disorder, including neurochemical, structural, and functional neuroimaging findings.

Original languageEnglish (US)
Pages (from-to)12-30
Number of pages19
JournalSeminars in clinical neuropsychiatry
Volume8
Issue number1
DOIs
StatePublished - Jan 2003
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

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