Modeling of bone failure by cohesive zone models

Thomas Siegmund, Matthew Allen, David Burr

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Cohesive zone models are a powerful tool for investigations of non-linear deformation and failure processes. For the nanoscale, the use of cohesive zone models is particularly attractive as the ratio of interface to volume is high, and because locally acting bonds between material components can become relevant. The present paper demonstrates the relevance of cohesive zone modelling approaches to the development of a nano-mechanical composite model of the mineralized collagen fibril, a fundamental building block of bone. As difficulties exist in determining the independent biomechan-ical effects of collagen cross-linking using in vitro and in vivo experiments, computational modeling can provide insight into the nanoscale processes. Stress-strain curves for mineralized collagen fibrils were obtained under tensile loading for various collagen cross-linking conditions. Our model predicts that the elastic deformation mode, the yield response and the final failure of the mineralized collagen fibril may depend significantly on the state of collagen cross-linking.

Original languageEnglish
Title of host publicationMechanics Down Under - Proceedings of the 22nd International Congress of Theoretical and Applied Mechanics, ICTAM 2008
Pages217-230
Number of pages14
DOIs
StatePublished - 2013
Event22nd International Congress of Theoretical and Applied Mechanics, ICTAM 2008 - Adelaide, SA, Australia
Duration: Aug 24 2008Aug 29 2008

Other

Other22nd International Congress of Theoretical and Applied Mechanics, ICTAM 2008
CountryAustralia
CityAdelaide, SA
Period8/24/088/29/08

Fingerprint

Collagen
Bone
Elastic deformation
Stress-strain curves
Composite materials
Experiments

ASJC Scopus subject areas

  • Mechanics of Materials

Cite this

Siegmund, T., Allen, M., & Burr, D. (2013). Modeling of bone failure by cohesive zone models. In Mechanics Down Under - Proceedings of the 22nd International Congress of Theoretical and Applied Mechanics, ICTAM 2008 (pp. 217-230) https://doi.org/10.1007/978-94-007-5968-8_14

Modeling of bone failure by cohesive zone models. / Siegmund, Thomas; Allen, Matthew; Burr, David.

Mechanics Down Under - Proceedings of the 22nd International Congress of Theoretical and Applied Mechanics, ICTAM 2008. 2013. p. 217-230.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Siegmund, T, Allen, M & Burr, D 2013, Modeling of bone failure by cohesive zone models. in Mechanics Down Under - Proceedings of the 22nd International Congress of Theoretical and Applied Mechanics, ICTAM 2008. pp. 217-230, 22nd International Congress of Theoretical and Applied Mechanics, ICTAM 2008, Adelaide, SA, Australia, 8/24/08. https://doi.org/10.1007/978-94-007-5968-8_14
Siegmund T, Allen M, Burr D. Modeling of bone failure by cohesive zone models. In Mechanics Down Under - Proceedings of the 22nd International Congress of Theoretical and Applied Mechanics, ICTAM 2008. 2013. p. 217-230 https://doi.org/10.1007/978-94-007-5968-8_14
Siegmund, Thomas ; Allen, Matthew ; Burr, David. / Modeling of bone failure by cohesive zone models. Mechanics Down Under - Proceedings of the 22nd International Congress of Theoretical and Applied Mechanics, ICTAM 2008. 2013. pp. 217-230
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