Molecular biology of basal and squamous cell carcinomas

Research output: Chapter in Book/Report/Conference proceedingChapter

21 Scopus citations


Basal cell carcinomas and Squamous cell carcinomas are the two most common human cancers. The incidence of these two types of cancer is estimated to double within 20 years. Identification of the key molecular events is critical in helping us design novel strategies to treat and to prevent these cancers. For example, identification of hedgehog signaling activation has opened up many opportunities for targeted therapy and prevention of basal cell carcinomas. Significant progress has also been made in our understanding of squamous cell carcinomas of the skin. In this chapter, we will focus on major recent developments in our understanding of basal cell carcinomas and squamous cell carcinomas at the molecular levels and their clinical implications.

Original languageEnglish (US)
Title of host publicationSunlight, Vitamin D and Skin Cancer
EditorsJorg Reichrath
Number of pages11
StatePublished - Dec 1 2008
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
ISSN (Print)0065-2598

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Xie, J. (2008). Molecular biology of basal and squamous cell carcinomas. In J. Reichrath (Ed.), Sunlight, Vitamin D and Skin Cancer (pp. 241-251). (Advances in Experimental Medicine and Biology; Vol. 624).