Molecular biology of basal and squamous cell carcinomas

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Basal cell carcinomas and Squamous cell carcinomas are the two most common human cancers. The incidence of these two types of cancer is estimated to double within 20 years. Identification of the key molecular events is critical in helping us design novel strategies to treat and to prevent these cancers. For example, identification of hedgehog signaling activation has opened up many opportunities for targeted therapy and prevention of basal cell carcinomas. Significant progress has also been made in our understanding of squamous cell carcinomas of the skin. In this chapter, we will focus on major recent developments in our understanding of basal cell carcinomas and squamous cell carcinomas at the molecular levels and their clinical implications.

Original languageEnglish (US)
Pages (from-to)241-251
Number of pages11
JournalAdvances in Experimental Medicine and Biology
Volume624
DOIs
StatePublished - 2008
Externally publishedYes

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Molecular biology
Basal Cell Carcinoma
Molecular Biology
Squamous Cell Carcinoma
Cells
Neoplasms
Skin
Chemical activation
Incidence
Epithelial Cells
Therapeutics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Molecular biology of basal and squamous cell carcinomas. / Xie, Jingwu.

In: Advances in Experimental Medicine and Biology, Vol. 624, 2008, p. 241-251.

Research output: Contribution to journalArticle

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