Molecular cardiology

New avenues for the diagnosis and treatment of cardiovascular disease

David R. Hathaway, Keith L. March

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

This review summarizes some of the major advances in the investigation of molecular mechanisms underlying both normal and abnormal cardiovascular function. Four major areas are highlighted including cardiac muscle, the blood vessel, atherosclerosis and thrombosis/thrombolysis. The remarkable strides in understanding multifactorial diseases such as atherosclerosis, and the development of innovative new therapies such as the use of thrombolytic agents produced by recombinant deoxyribonucleic acid (DNA) technology, are noted. Moreover, it is concluded that the past decade of basic research has provided a solid framework for improvements in the diagnosis and therapy of other forms of cardiovascular disease as well. An evaluation of current trends in basic cardiovascular research suggests that diagnostic and therapeutic approaches to disease will increasingly target specific molecular processes underlyinh the pathophysiologic state.

Original languageEnglish
Pages (from-to)265-282
Number of pages18
JournalJournal of the American College of Cardiology
Volume13
Issue number2
DOIs
StatePublished - 1989

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Cardiology
Atherosclerosis
Cardiovascular Diseases
Investigational Therapies
Fibrinolytic Agents
Research
Blood Vessels
Myocardium
Thrombosis
Technology
DNA
Therapeutics

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Molecular cardiology : New avenues for the diagnosis and treatment of cardiovascular disease. / Hathaway, David R.; March, Keith L.

In: Journal of the American College of Cardiology, Vol. 13, No. 2, 1989, p. 265-282.

Research output: Contribution to journalArticle

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