Molecular mechanisms and therapeutic strategies of tumor-associated angiogenesis

S. F. Zhuang, Q. Z. Ye

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Tumor-associated angiogenesis plays a pivotal role in the growth and metastasis of tumors. Many angiogenesis factors (including activators and inhibitors) participate in modulating tumor-associated angiogenesis. Through studying the mechanisms of angiogenesis regulation by angiogenesis factors, we may find ways to control the angiogenesis process in tumors as novel approaches to cancer treatment. In this review, we report the recent progress in mechanistic studies of angiogenesis and therapeutic approaches to cancer treatment through antiangiogenesis.

Original languageEnglish (US)
Pages (from-to)128-132
Number of pages5
JournalChinese Pharmacological Bulletin
Volume16
Issue number2
StatePublished - Jan 1 2000
Externally publishedYes

Keywords

  • Angiogenesis activators
  • Angiogenesis inhibitors
  • Antiangiogenic therapy
  • Tumor-associated angiogenesis

ASJC Scopus subject areas

  • Pharmacology

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