Molecular pathology of the central nervous system

Brent T. Harris, Eyas M. Hattab

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

In direct reflection of the vastly improved molecular interrogation techniques available today, we have recently witnessed an explosion of new emerging information concerning the molecular genetics of central nervous system (CNS) diseases, involving both neoplastic and neurodegenerative disorders. This has had immediate diagnostic, prognostic and predictive effects on various CNS diseases. The promise of targeted therapy against newly identified molecules acts only as an added motivation to furthering the study of these disease entities. In this chapter, we provide an overview of the most commonly encountered CNS tumors and neurodegenerative conditions with particular emphasis on the molecular alterations encountered in these entities, their potential applications and possible therapeutic targets.

Original languageEnglish (US)
Title of host publicationMolecular Surgical Pathology
PublisherSpringer New York
Pages357-405
Number of pages49
Volume9781461449003
ISBN (Print)9781461449003, 1461448999, 9781461448990
DOIs
StatePublished - May 1 2013

Fingerprint

Molecular Pathology
Central Nervous System Diseases
Central Nervous System
Central Nervous System Neoplasms
Explosions
Neurodegenerative Diseases
Molecular Biology
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Harris, B. T., & Hattab, E. M. (2013). Molecular pathology of the central nervous system. In Molecular Surgical Pathology (Vol. 9781461449003, pp. 357-405). Springer New York. https://doi.org/10.1007/978-1-4614-4900-3_16

Molecular pathology of the central nervous system. / Harris, Brent T.; Hattab, Eyas M.

Molecular Surgical Pathology. Vol. 9781461449003 Springer New York, 2013. p. 357-405.

Research output: Chapter in Book/Report/Conference proceedingChapter

Harris, BT & Hattab, EM 2013, Molecular pathology of the central nervous system. in Molecular Surgical Pathology. vol. 9781461449003, Springer New York, pp. 357-405. https://doi.org/10.1007/978-1-4614-4900-3_16
Harris BT, Hattab EM. Molecular pathology of the central nervous system. In Molecular Surgical Pathology. Vol. 9781461449003. Springer New York. 2013. p. 357-405 https://doi.org/10.1007/978-1-4614-4900-3_16
Harris, Brent T. ; Hattab, Eyas M. / Molecular pathology of the central nervous system. Molecular Surgical Pathology. Vol. 9781461449003 Springer New York, 2013. pp. 357-405
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