Mortality from lower respiratory infection in nursing home residents: A pilot prospective community-based study

David R. Mehr, Steven C. Zweig, Robin L. Kruse, Lori Popejoy, Darla Horman, Deanna Willis, M. Elaine Doyle

Research output: Contribution to journalArticle

44 Scopus citations


BACKGROUND. Lower respiratory infections (LRI) are an important cause of morbidity, mortality, and hospitalization of nursing home residents, yet treatment recommendations have primarily been based on the minority who are hospitalized. We sought to prospectively evaluate risk factors for mortality from LRI in community nursing home residents. METHODS. We studied residents of 10 central Missouri nursing homes (910 beds) from January 1994 to September 1994. Attending physicians authorized nurse evaluations of ill residents who showed symptoms of an LRI. Those residents who met the study definition of LRI received a more detailed assessment and follow ups at 30 and 90 days. RESULTS. The 231 evaluations identified 141 LRIs in 121 individuals. Sixteen (11%) residents died within 30 days of evaluation. The most important univariate predictor of 30-day mortality was severe activities of daily living (ADL) dependency (relative risk = 8.8, 95% confidence interval, 2.55 - 30.1). Several other clinical and laboratory findings were also significant predictors. In multivariable logistic regression, ADL dependency, respiratory rate, and pneumonia on chest radiograph independently predicted mortality; the model showed good discriminating ability (c=.83). CONCLUSIONS. For nursing home residents with LRI, ADL dependency is an important mortality predictor. Further research with a larger sample should lead to a useful prediction rule for outcome from nursing home-acquired LRI.

Original languageEnglish (US)
Pages (from-to)298-304
Number of pages7
JournalJournal of Family Practice
Issue number4
StatePublished - Oct 1 1998



  • Activities of daily living
  • Nursing homes
  • Respiratory tract infections
  • Risk factors

ASJC Scopus subject areas

  • Family Practice

Cite this

Mehr, D. R., Zweig, S. C., Kruse, R. L., Popejoy, L., Horman, D., Willis, D., & Doyle, M. E. (1998). Mortality from lower respiratory infection in nursing home residents: A pilot prospective community-based study. Journal of Family Practice, 47(4), 298-304.