Motility and functional disorders of the stomach

Diagnosis and management of functional dyspepsia and gastroparesis

John Wo, Henry P. Parkman

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Functional dyspepsia and gastroparesis are the most common functional and motility disorders of the stomach. Functional dyspepsia is a heterogeneous syndrome with multiple pathophysiologies that refers to symptoms originating in the gastroduodenal region in the absence of an organic cause. Patients with functional dyspepsia may present with primarily postprandial symptoms including fullness, early satiety, and bloating, while other patients may present with the predominant symptom of epigastric pain. Gastroparesis is a symptomatic chronic disorder characterized by delayed gastric emptying without mechanical obstruction. Although gastroparesis is often caused by diabetes and prior gastric surgery, the underlying cause may not be found in many patients. Clinical manifestation of gastroparesis is variable. Patients present with debilitating nausea and vomiting resulting in weight loss and dehydration. Other patients may present with postprandial symptoms of postprandial fullness, early satiety, and effortless regurgitation. In this review, an update on the underlying mechanisms, clinical features, diagnostic evaluation, and treatment for functional dyspepsia and gastroparesis is provided.

Original languageEnglish (US)
Pages (from-to)23-48
Number of pages26
JournalPractical Gastroenterology
Volume30
Issue number12
StatePublished - Dec 2006
Externally publishedYes

Fingerprint

Gastroparesis
Dyspepsia
Stomach
Gastric Emptying
Dehydration
Nausea
Vomiting
Weight Loss
Pain

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Motility and functional disorders of the stomach : Diagnosis and management of functional dyspepsia and gastroparesis. / Wo, John; Parkman, Henry P.

In: Practical Gastroenterology, Vol. 30, No. 12, 12.2006, p. 23-48.

Research output: Contribution to journalArticle

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