MsFLASH participants priorities for alleviating menopausal symptoms

Janet Carpenter, N. F. Woods, Julie Otte, K. A. Guthrie, C. Hohensee, K. M. Newton, H. Joffe, L. Cohen, B. Sternfeld, R. J. Lau, S. D. Reed, A. Z. Lacroix

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

To describe self-reported menopausal symptom priorities and their association with demographics and other symptoms among participants in an intervention trial for vasomotor symptoms (VMS).Methods Cross-sectional study embedded in the MsFLASH 02 trial, a three-by-two factorial design of yoga vs. exercise vs. usual activity and omega-3-fatty acid vs. placebo. At baseline, women (n = 354) completed hot flush diaries, a card sort task to prioritize symptoms they would most like to alleviate, and standardized questionnaires.Results The most common symptom priorities were: VMS (n = 322), sleep (n = 191), concentration (n = 140), and fatigue (n = 116). In multivariate models, women who chose VMS as their top priority symptom (n = 210) reported significantly greater VMS severity (p = 0.004) and never smoking (p = 0.012), and women who chose sleep as their top priority symptom (n = 100) were more educated (p ≤ 0.001) and had worse sleep quality (p <0.001). ROC curves identified sleep scale scores that were highly predictive of ranking sleep as a top priority symptom.Conclusions Among women entering an intervention trial for VMS and with relatively low prevalence of depression and anxiety, VMS was the priority symptom for treatment. A card sort may be a valid tool for quickly assessing symptom priorities in clinical practice and research.

Original languageEnglish (US)
Pages (from-to)859-866
Number of pages8
JournalClimacteric
Volume18
Issue number6
DOIs
StatePublished - Nov 2 2015

Fingerprint

Sleep
Yoga
Omega-3 Fatty Acids
ROC Curve
Fatigue
Anxiety
Cross-Sectional Studies
Smoking
Placebos
Demography
Exercise
Depression
Research
Therapeutics

Keywords

  • Cognitive Functioning
  • Fatigue
  • Menopause
  • Sleep Disturbances
  • Symptoms
  • Vasomotor Symptoms

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Carpenter, J., Woods, N. F., Otte, J., Guthrie, K. A., Hohensee, C., Newton, K. M., ... Lacroix, A. Z. (2015). MsFLASH participants priorities for alleviating menopausal symptoms. Climacteric, 18(6), 859-866. https://doi.org/10.3109/13697137.2015.1083003

MsFLASH participants priorities for alleviating menopausal symptoms. / Carpenter, Janet; Woods, N. F.; Otte, Julie; Guthrie, K. A.; Hohensee, C.; Newton, K. M.; Joffe, H.; Cohen, L.; Sternfeld, B.; Lau, R. J.; Reed, S. D.; Lacroix, A. Z.

In: Climacteric, Vol. 18, No. 6, 02.11.2015, p. 859-866.

Research output: Contribution to journalArticle

Carpenter, J, Woods, NF, Otte, J, Guthrie, KA, Hohensee, C, Newton, KM, Joffe, H, Cohen, L, Sternfeld, B, Lau, RJ, Reed, SD & Lacroix, AZ 2015, 'MsFLASH participants priorities for alleviating menopausal symptoms', Climacteric, vol. 18, no. 6, pp. 859-866. https://doi.org/10.3109/13697137.2015.1083003
Carpenter, Janet ; Woods, N. F. ; Otte, Julie ; Guthrie, K. A. ; Hohensee, C. ; Newton, K. M. ; Joffe, H. ; Cohen, L. ; Sternfeld, B. ; Lau, R. J. ; Reed, S. D. ; Lacroix, A. Z. / MsFLASH participants priorities for alleviating menopausal symptoms. In: Climacteric. 2015 ; Vol. 18, No. 6. pp. 859-866.
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