Mucin-like changes in keloids

D. Santa Cruz, Thomas Ulbright

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Six of 125 keloids of the earlobe demonstrated a peculiar accumulation of mucinous material within their stroma. The six patients had all received prior injections of a corticosteroid compound. The histopathologic picture is characterized by irregularly contoured pools of amorphous eosinophilic material surrounded by a variable granulomatous response of multinucleate giant cells and bubbly histiocytes. Histochemical studies demonstrated that the material is different from the hyaluronic acid-rich substances of the usual forms of cutaneous mucinoses. The lesion is similar to but distinct from that previously described to occur in nasal mucosa injected with corticosteroids. Its recognition and correlation with clinical history should prevent confusion with other entities.

Original languageEnglish (US)
Pages (from-to)18-22
Number of pages5
JournalAmerican Journal of Clinical Pathology
Volume75
Issue number1
StatePublished - 1981
Externally publishedYes

Fingerprint

Keloid
Mucins
Adrenal Cortex Hormones
Mucinoses
Histiocytes
Nasal Mucosa
Giant Cells
Hyaluronic Acid
Skin
Injections

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Mucin-like changes in keloids. / Santa Cruz, D.; Ulbright, Thomas.

In: American Journal of Clinical Pathology, Vol. 75, No. 1, 1981, p. 18-22.

Research output: Contribution to journalArticle

Santa Cruz, D. ; Ulbright, Thomas. / Mucin-like changes in keloids. In: American Journal of Clinical Pathology. 1981 ; Vol. 75, No. 1. pp. 18-22.
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