Mucin-like changes in keloids

D. Santa Cruz, T. M. Ulbright

Research output: Contribution to journalArticle

11 Scopus citations


Six of 125 keloids of the earlobe demonstrated a peculiar accumulation of mucinous material within their stroma. The six patients had all received prior injections of a corticosteroid compound. The histopathologic picture is characterized by irregularly contoured pools of amorphous eosinophilic material surrounded by a variable granulomatous response of multinucleate giant cells and bubbly histiocytes. Histochemical studies demonstrated that the material is different from the hyaluronic acid-rich substances of the usual forms of cutaneous mucinoses. The lesion is similar to but distinct from that previously described to occur in nasal mucosa injected with corticosteroids. Its recognition and correlation with clinical history should prevent confusion with other entities.

Original languageEnglish (US)
Pages (from-to)18-22
Number of pages5
JournalAmerican journal of clinical pathology
Issue number1
StatePublished - Jan 1 1981
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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