Multi-Institutional Review of Outcomes and Complications of Robot-Assisted Laparoscopic Extravesical Ureteral Reimplantation for Treatment of Primary Vesicoureteral Reflux in Children

William R. Boysen, Jonathan S. Ellison, Christina Kim, Chester J. Koh, Paul Noh, Benjamin Whittam, Blake Palmer, Aseem Shukla, Andrew Kirsch, Mohan S. Gundeti

Research output: Contribution to journalArticle

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Abstract

Purpose Robot-assisted laparoscopic extravesical ureteral reimplantation has been proposed as a minimally invasive alternative to open ureteral reimplantation for correcting primary vesicoureteral reflux in children. However, in the current literature there are conflicting data regarding the safety and efficacy of this approach. Amid ongoing debate we analyzed outcomes and complications from this procedure in a large multi-institutional cohort. Materials and Methods We reviewed the records of children who underwent robot-assisted laparoscopic extravesical ureteral reimplantation at 9 academic centers from 2005 to 2014. Radiographic failure was defined as persistent vesicoureteral reflux on postoperative voiding cystourethrogram or radionuclide cystogram. Complications were graded using the Clavien-Dindo scale. Results A total of 260 patients (363 ureters) underwent robot-assisted laparoscopic extravesical ureteral reimplantation for primary vesicoureteral reflux during the study period. The cohort included 90 patients with either duplex ureter (42), failed endoscopic treatment (40) or concomitant diverticulectomy (8). Of the 280 ureters with postoperative voiding cystourethrogram or radionuclide cystogram available radiographic resolution was seen in 246 (87.9%). There were 25 complications overall (9.6%), with 7 grade 3 complications (2.7%) and no grade 4 or 5 complications. Four patients (3.9%) had transient urinary retention following bilateral reimplantation. Conclusions Robot-assisted laparoscopic extravesical ureteral reimplantation has a low complication rate consistent with published series of open ureteral reimplantation. Radiographic success rates are approaching those of the open procedure but continue to fall short of the gold standard approach. These findings necessitate critical thinking regarding potential technique improvements and further prospective investigation into the efficacy of this procedure.

Original languageEnglish (US)
Pages (from-to)1555-1561
Number of pages7
JournalJournal of Urology
Volume197
Issue number6
DOIs
StatePublished - Jun 1 2017

Fingerprint

Vesico-Ureteral Reflux
Replantation
Ureter
Radioisotopes
Therapeutics
Urinary Retention
Safety

Keywords

  • minimally invasive surgical procedures
  • replantation
  • robotic surgical procedures
  • ureter
  • vesico-ureteral reflux

ASJC Scopus subject areas

  • Urology

Cite this

Multi-Institutional Review of Outcomes and Complications of Robot-Assisted Laparoscopic Extravesical Ureteral Reimplantation for Treatment of Primary Vesicoureteral Reflux in Children. / Boysen, William R.; Ellison, Jonathan S.; Kim, Christina; Koh, Chester J.; Noh, Paul; Whittam, Benjamin; Palmer, Blake; Shukla, Aseem; Kirsch, Andrew; Gundeti, Mohan S.

In: Journal of Urology, Vol. 197, No. 6, 01.06.2017, p. 1555-1561.

Research output: Contribution to journalArticle

Boysen, William R. ; Ellison, Jonathan S. ; Kim, Christina ; Koh, Chester J. ; Noh, Paul ; Whittam, Benjamin ; Palmer, Blake ; Shukla, Aseem ; Kirsch, Andrew ; Gundeti, Mohan S. / Multi-Institutional Review of Outcomes and Complications of Robot-Assisted Laparoscopic Extravesical Ureteral Reimplantation for Treatment of Primary Vesicoureteral Reflux in Children. In: Journal of Urology. 2017 ; Vol. 197, No. 6. pp. 1555-1561.
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abstract = "Purpose Robot-assisted laparoscopic extravesical ureteral reimplantation has been proposed as a minimally invasive alternative to open ureteral reimplantation for correcting primary vesicoureteral reflux in children. However, in the current literature there are conflicting data regarding the safety and efficacy of this approach. Amid ongoing debate we analyzed outcomes and complications from this procedure in a large multi-institutional cohort. Materials and Methods We reviewed the records of children who underwent robot-assisted laparoscopic extravesical ureteral reimplantation at 9 academic centers from 2005 to 2014. Radiographic failure was defined as persistent vesicoureteral reflux on postoperative voiding cystourethrogram or radionuclide cystogram. Complications were graded using the Clavien-Dindo scale. Results A total of 260 patients (363 ureters) underwent robot-assisted laparoscopic extravesical ureteral reimplantation for primary vesicoureteral reflux during the study period. The cohort included 90 patients with either duplex ureter (42), failed endoscopic treatment (40) or concomitant diverticulectomy (8). Of the 280 ureters with postoperative voiding cystourethrogram or radionuclide cystogram available radiographic resolution was seen in 246 (87.9{\%}). There were 25 complications overall (9.6{\%}), with 7 grade 3 complications (2.7{\%}) and no grade 4 or 5 complications. Four patients (3.9{\%}) had transient urinary retention following bilateral reimplantation. Conclusions Robot-assisted laparoscopic extravesical ureteral reimplantation has a low complication rate consistent with published series of open ureteral reimplantation. Radiographic success rates are approaching those of the open procedure but continue to fall short of the gold standard approach. These findings necessitate critical thinking regarding potential technique improvements and further prospective investigation into the efficacy of this procedure.",
keywords = "minimally invasive surgical procedures, replantation, robotic surgical procedures, ureter, vesico-ureteral reflux",
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AU - Ellison, Jonathan S.

AU - Kim, Christina

AU - Koh, Chester J.

AU - Noh, Paul

AU - Whittam, Benjamin

AU - Palmer, Blake

AU - Shukla, Aseem

AU - Kirsch, Andrew

AU - Gundeti, Mohan S.

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AB - Purpose Robot-assisted laparoscopic extravesical ureteral reimplantation has been proposed as a minimally invasive alternative to open ureteral reimplantation for correcting primary vesicoureteral reflux in children. However, in the current literature there are conflicting data regarding the safety and efficacy of this approach. Amid ongoing debate we analyzed outcomes and complications from this procedure in a large multi-institutional cohort. Materials and Methods We reviewed the records of children who underwent robot-assisted laparoscopic extravesical ureteral reimplantation at 9 academic centers from 2005 to 2014. Radiographic failure was defined as persistent vesicoureteral reflux on postoperative voiding cystourethrogram or radionuclide cystogram. Complications were graded using the Clavien-Dindo scale. Results A total of 260 patients (363 ureters) underwent robot-assisted laparoscopic extravesical ureteral reimplantation for primary vesicoureteral reflux during the study period. The cohort included 90 patients with either duplex ureter (42), failed endoscopic treatment (40) or concomitant diverticulectomy (8). Of the 280 ureters with postoperative voiding cystourethrogram or radionuclide cystogram available radiographic resolution was seen in 246 (87.9%). There were 25 complications overall (9.6%), with 7 grade 3 complications (2.7%) and no grade 4 or 5 complications. Four patients (3.9%) had transient urinary retention following bilateral reimplantation. Conclusions Robot-assisted laparoscopic extravesical ureteral reimplantation has a low complication rate consistent with published series of open ureteral reimplantation. Radiographic success rates are approaching those of the open procedure but continue to fall short of the gold standard approach. These findings necessitate critical thinking regarding potential technique improvements and further prospective investigation into the efficacy of this procedure.

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