Multi-modal assessment in Alzheimer's disease. ADL in relation to PET, MRI and neuropsychology.

E. Souder, A. J. Saykin, A. Alavi

Research output: Contribution to journalArticle

2 Scopus citations


Alzheimer's disease (AD) causes a deterioration in functional status which may best be understood as a multi-dimensional concept. Results of multi-modal functional assessment in two patients with probable AD and comparable Mini-Mental State Examination scores demonstrated the heterogeneity of disease profiles and individual variations in functional status. Measures included direct assessment of ADL performance (SAILS), self and family perception of "current" and "best ever" functioning (NBFADL-60), neuropsychological test battery, magnetic resonance imaging (MRI) and positron emission tomography (FDG-PET). The multi-modal assessment yielded complementary information, and permitted correlation of physiological and behavioral data. Future studies should examine the potential heuristic and clinical utility of this approach.

Original languageEnglish (US)
Pages (from-to)7-13
Number of pages7
JournalJournal of gerontological nursing
Issue number9
StatePublished - Sep 1 1995
Externally publishedYes

ASJC Scopus subject areas

  • Nursing(all)
  • Gerontology

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