Multimodal therapy in the treatment of carcinoma of the uterine cervix

E. A. Case, F. B. Stehman

Research output: Contribution to journalArticle

1 Scopus citations


What is the best treatment for patients with locally advanced cervical cancer? Radiation therapy with external beam and brachytherapy implants has long been the standard in North America. Much investigation has been conducted regarding treatment of this disease, and researchers have demonstrated the importance of appropriate scheduling, dosing, and field design. The authors of five recently published randomized clinical trials strongly suggest that radiation with concurrent chemotherapy that utilizes cisplatin should be the new treatment standard for patients with locally advanced cervical cancer. Carcinoma of the uterine cervix remains a major health problem for women worldwide. In the United States, early detection of cervical cancer has been made possible by the development of Papanicolaou's smear, which has significantly reduced the mortality associated with the disease. Still, there will be 12,900 American women diagnosed with invasive cervical cancer in 2001. Most of these cancers will be found in women who had not been screened regularly. In addition, cervical cancer is the second most frequent cancer among women worldwide and the most frequent cancer among women in Africa, Asia, and South America.

Original languageEnglish (US)
Pages (from-to)323-328
Number of pages6
JournalOncology Spectrums
Issue number5
StatePublished - Jan 1 2001


ASJC Scopus subject areas

  • Health Policy

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