Multiple subpial transection for Landau-Kleffner syndrome.

J. M. Buelow, P. Aydelott, D. M. Pierz, B. Heck

Research output: Contribution to journalReview article

7 Scopus citations


Landau-Kleffner syndrome (LKS) is an acquired epileptic aphasia caused by a lesion in the speech centers of the cerebral cortex during a critical period of childhood development. Characteristics of LKS include language deterioration, seizure disorders, and severe electroencephalogram abnormalities. Multiple subpial transection (MST) is a surgical procedure that eliminates seizure activity in the cerebral cortex while preserving the child's normal cortical functions of speech, movement, primary sensation, and memory. This article presents a summary of clinical studies on LKS and discusses the diagnosis of LKS, traditional medical treatments, patient selection for MST procedures, and perioperative care of children undergoing MST procedures.

Original languageEnglish (US)
Pages (from-to)725
Number of pages1
JournalAORN journal
Issue number4
StatePublished - Apr 1996

ASJC Scopus subject areas

  • Medical–Surgical

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    Buelow, J. M., Aydelott, P., Pierz, D. M., & Heck, B. (1996). Multiple subpial transection for Landau-Kleffner syndrome. AORN journal, 63(4), 725.