Myasthenia gravis and Lambert-Eaton syndrome

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9 Scopus citations

Abstract

Myasthenia gravis is a common autoimmune disorder characterized by the presence of pathogenic antibodies directed against the acetylcholine receptor. Patients present with variable degrees and distribution of fluctuating weakness at times life threatening. Clinical manifestations, establishment of diagnosis, the natural history of myasthenia gravis, and therapeutic options are herein reviewed. Far less common is Lambert-Eaton syndrome (the myasthenic syndrome), another autoimmune disorder due to the presence of antibodies directed against the PQ-type voltage-gated calcium channels. Clinical features and treatment options are summarized.

Original languageEnglish (US)
Pages (from-to)57-68
Number of pages12
JournalTherapeutic Apheresis
Volume6
Issue number1
DOIs
StatePublished - Mar 23 2002

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Keywords

  • Immunotherapy of neuromuscular disease
  • Lambert-Eaton syndrome
  • Myasthenia gravis
  • Plasma exchange

ASJC Scopus subject areas

  • Medicine(all)

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