Myasthenia gravis and Lambert-Eaton syndrome

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Myasthenia gravis is a common autoimmune disorder characterized by the presence of pathogenic antibodies directed against the acetylcholine receptor. Patients present with variable degrees and distribution of fluctuating weakness at times life threatening. Clinical manifestations, establishment of diagnosis, the natural history of myasthenia gravis, and therapeutic options are herein reviewed. Far less common is Lambert-Eaton syndrome (the myasthenic syndrome), another autoimmune disorder due to the presence of antibodies directed against the PQ-type voltage-gated calcium channels. Clinical features and treatment options are summarized.

Original languageEnglish
Pages (from-to)57-68
Number of pages12
JournalTherapeutic Apheresis
Volume6
Issue number1
DOIs
StatePublished - 2002

Fingerprint

Lambert-Eaton Myasthenic Syndrome
Myasthenia Gravis
Antibodies
Cholinergic Receptors
Calcium Channels
Therapeutics

Keywords

  • Immunotherapy of neuromuscular disease
  • Lambert-Eaton syndrome
  • Myasthenia gravis
  • Plasma exchange

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Myasthenia gravis and Lambert-Eaton syndrome. / Pascuzzi, Robert.

In: Therapeutic Apheresis, Vol. 6, No. 1, 2002, p. 57-68.

Research output: Contribution to journalArticle

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