Myocardial infarction/injury is relatively common at presentation of acute thrombotic thrombocytopenic purpura: The Indiana University experience

Leo J. McCarthy, Constance F M Danielson, Elaine M. Skipworth, Shelley L. Peters, Charles C. Miraglia, Asok Antony

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Although widespread vascular thrombosis is common in thrombotic thrombocytopenic purpura (TTP), there have been no prospective studies on the extent of injury to specific organs. Following successful resuscitation and plasma exchange of an index patient with widespread organ dysfunction, cardiogenic shock, and elevated cardiac troponin-I levels, we prospectively studied and identified 2 more individuals (of 10 consecutive patients) with evidence of myocardial injury/infarction at presentation of acute TTP. These data suggest that cardiac troponin-I measurements should be considered during initial evaluation of all patients with acute TTP.

Original languageEnglish
Pages (from-to)2-4
Number of pages3
JournalTherapeutic Apheresis
Volume6
Issue number1
DOIs
StatePublished - 2002

Fingerprint

Thrombotic Thrombocytopenic Purpura
Troponin I
Myocardial Infarction
Wounds and Injuries
Plasma Exchange
Cardiogenic Shock
Resuscitation
Blood Vessels
Thrombosis
Prospective Studies

Keywords

  • Cardiac troponin-I
  • Cardiogenic shock
  • Myocardial infarction
  • Plasma exchange
  • Solvent detergent plasma
  • Thrombotic thrombocytopenic purpura

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Myocardial infarction/injury is relatively common at presentation of acute thrombotic thrombocytopenic purpura : The Indiana University experience. / McCarthy, Leo J.; Danielson, Constance F M; Skipworth, Elaine M.; Peters, Shelley L.; Miraglia, Charles C.; Antony, Asok.

In: Therapeutic Apheresis, Vol. 6, No. 1, 2002, p. 2-4.

Research output: Contribution to journalArticle

McCarthy, Leo J. ; Danielson, Constance F M ; Skipworth, Elaine M. ; Peters, Shelley L. ; Miraglia, Charles C. ; Antony, Asok. / Myocardial infarction/injury is relatively common at presentation of acute thrombotic thrombocytopenic purpura : The Indiana University experience. In: Therapeutic Apheresis. 2002 ; Vol. 6, No. 1. pp. 2-4.
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