Myocyte and myogenic stem cell transplantation in the heart

Joshua D. Dowell, Michael Rubart-von der Lohe, Kishore B S Pasumarthi, Mark Soonpaa, Loren Field

Research output: Contribution to journalArticle

216 Citations (Scopus)

Abstract

Cellular transplantation is emerging as a potential mechanism with which to augment myocyte number in diseased hearts. To date a number of cell types have been shown to successfully engraft into the myocardium, including fetal, neonatal, and embryonic stem cell-derived cardiomyocytes, skeletal myoblasts, and stem cells with apparent cardiomyogenic potential. Here we provide a review of studies wherein myocytes or stem cells with myogenic potential have been transplanted into the heart. In addition, issues pertaining to the tracking and functional consequences of cell transplantation are discussed.

Original languageEnglish
Pages (from-to)336-350
Number of pages15
JournalCardiovascular Research
Volume58
Issue number2
DOIs
StatePublished - May 1 2003

Fingerprint

Stem Cell Transplantation
Muscle Cells
Stem Cells
Fetal Stem Cells
Skeletal Myoblasts
Cell Transplantation
Embryonic Stem Cells
Cardiac Myocytes
Heart Diseases
Myocardium
Cell Count
Transplantation

Keywords

  • Cardiomyocytes
  • Cellular transplantation
  • Heart failure
  • Skeletal myoblasts
  • Stem cells

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Myocyte and myogenic stem cell transplantation in the heart. / Dowell, Joshua D.; Rubart-von der Lohe, Michael; Pasumarthi, Kishore B S; Soonpaa, Mark; Field, Loren.

In: Cardiovascular Research, Vol. 58, No. 2, 01.05.2003, p. 336-350.

Research output: Contribution to journalArticle

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