Naltrexone and brief counseling to reduce heavy drinking in hazardous drinkers

Dena Davidson, Chandan Saha, Stephanie Scifres, Joanne Fyffe, Sean O'Connor, Christopher Selzer

Research output: Contribution to journalArticle

19 Scopus citations


The present study examined the utility of daily naltrexone for decreasing alcohol drinking in hazardous drinkers. Forty-one participants participated in a 10-week trial and received 30 min of brief counseling on the first and second week of treatment, as well as a daily dose of 50 mg of naltrexone throughout the trial. Overall, naltrexone-treated participants did not show the same degree of improvement on drinking outcomes as placebo-treated participants. The placebo group drank fewer drinks per drinking day and achieved more abstinence days than the naltrexone group. Craving was also lower for the placebo group. The groups were not balanced on gender or family history of alcoholism and this may explain the lack of effect of naltrexone on the drinking outcomes.

Original languageEnglish (US)
Pages (from-to)1253-1258
Number of pages6
JournalAddictive Behaviors
Issue number6
StatePublished - Aug 1 2004


  • Hazardous drinkers
  • Heavy drinking
  • Naltrexone

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology

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