Natural history of cholelithiasis in patients with alcoholic cirrhosis (cholelithiasis in cirrhotic patients)

Gary Dunnington, E. Alfrey, R. Sampliner, F. Kogan, C. Putnam

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

To assess the natural history of cholelithiasis in patients with cirrhosis, 32 charts coded for both diseases were retrospectively reviewed. Cholecystectomy was performed in 22 patients. Only two patients met criteria for acute cholecystitis and two patients had suspected choledocholithiasis. Despite the high incidence of preoperative jaundice (32%), no common duct stones were documented. There was no operative mortality. The complication rate was 45%. In 10 patients not operated upon, two patients died of liver failure and the remaining eight patients are alive 8 months to 13 years after diagnosis (mean: 46 months) with no active biliary disease. It is concluded that: (1) jaundice in this subpopulation most often reflects hepatocellular injury and rarely biliary tract obstruction, (2) there appears to be a much lower incidence of acute cholecystitis and choledocholithiasis in cirrhotic patients with cholelithiasis than in the normal population, and (3) patients with cirrhosis and asymptomatic cholelithiasis can be safely managed without operation.

Original languageEnglish (US)
Pages (from-to)226-229
Number of pages4
JournalAnnals of Surgery
Volume205
Issue number3
StatePublished - 1987
Externally publishedYes

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Alcoholic Liver Cirrhosis
Cholelithiasis
Choledocholithiasis
Acute Cholecystitis
Jaundice
Fibrosis
Incidence
Liver Failure
Biliary Tract
Cholecystectomy
Mortality

ASJC Scopus subject areas

  • Surgery

Cite this

Natural history of cholelithiasis in patients with alcoholic cirrhosis (cholelithiasis in cirrhotic patients). / Dunnington, Gary; Alfrey, E.; Sampliner, R.; Kogan, F.; Putnam, C.

In: Annals of Surgery, Vol. 205, No. 3, 1987, p. 226-229.

Research output: Contribution to journalArticle

Dunnington, Gary ; Alfrey, E. ; Sampliner, R. ; Kogan, F. ; Putnam, C. / Natural history of cholelithiasis in patients with alcoholic cirrhosis (cholelithiasis in cirrhotic patients). In: Annals of Surgery. 1987 ; Vol. 205, No. 3. pp. 226-229.
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