Near infrared spectroscopy (NIRS) distinguishes seizure types

Deborah Sokol, Omkar Markand, E. C. Daly, T. G. Luerssen, M. D. Malkoff

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Near infrared spectroscopy (NIRS) is a noninvasive method for bedside measurement of cerebral oxygenation (SaO 2). The purpose of this study was to establish differences in SaO 2 for complex partial seizures (CPS) and rapidly secondarily generalized CPS (RCPS). We studied eight adults with medically refractory epilepsy undergoing evaluation for temporal lobectomy. We continually measured cerebral SaO 2 via a Somanetic Invos 3100a cerebral oximeter, pre-ictal (5 minutes), ictal, immediate (30 seconds) post-ictal, and late post-ictal (5 minutes after ictus). Seventeen seizures (12 CPS, four RCPS and one subclinical) were recorded in eight patients. The percentage change in cerebral SaO 2 from pre-ictal to ictal periods was derived. Cerebral SaO 2 increased (percentage change, mean: 16.6, SD: 13.9) for CPS and decreased (percentage change, mean: 51.1, SD: 18.1) for RCPS. No change in cerebral oximetry was recorded for the subclinical seizure. Post-ictal (immediate and late) increase in cerebral SaO 2 was seen for 11 of the 17 seizures (nine CPS and two RCPS). Peripheral SaO 2 rose greater than 93% for all CPS and the subclinical seizure, but decreased between 78 and 84% during RCPS. These results suggest NIRS distinguishes cerebral SaO 2 patterns between CPS and RCPS. The decrease in peripheral SaO 2, however, may account for the decrease in cerebral SaO 2 seen in generalized seizures. (C) 2000 BEA Trading Ltd.

Original languageEnglish (US)
Pages (from-to)323-327
Number of pages5
JournalSeizure
Volume9
Issue number5
DOIs
StatePublished - 2000
Externally publishedYes

Fingerprint

Near-Infrared Spectroscopy
Seizures
Stroke
Partial Epilepsy
Oximetry
Epilepsy

Keywords

  • Epilepsy
  • Near infrared spectroscopy
  • NIRS
  • Seizures

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Psychology(all)

Cite this

Near infrared spectroscopy (NIRS) distinguishes seizure types. / Sokol, Deborah; Markand, Omkar; Daly, E. C.; Luerssen, T. G.; Malkoff, M. D.

In: Seizure, Vol. 9, No. 5, 2000, p. 323-327.

Research output: Contribution to journalArticle

Sokol, Deborah ; Markand, Omkar ; Daly, E. C. ; Luerssen, T. G. ; Malkoff, M. D. / Near infrared spectroscopy (NIRS) distinguishes seizure types. In: Seizure. 2000 ; Vol. 9, No. 5. pp. 323-327.
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