Neonatal systemic juvenile xanthogranuloma with an ominous presentation and successful treatment

Rong Fan, Jihong Sun

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

This case report originated from a case of neonatal multisystemic juvenile xanthogranuloma (JXG). The patient presented with blue muffin rush, cervical mass, bone destruction, lung nodule, hepatosplenomegaly, and coagulopathy and was successfully treated with Langerhans cell histiocytosis (LCH) based chemotherapy treatment. Similar cases in literature were reviewed and it seems that JXG, a relatively benign entity, when presented in its systemic form with liver involvement, could have an aggressive course and portend quite poor prognosis. Challenges and special consideration of the diagnosis, treatment, and future case observation are discussed.

Original languageEnglish
Pages (from-to)157-161
Number of pages5
JournalClinical Medicine Insights: Oncology
Volume5
DOIs
StatePublished - 2011

Fingerprint

Juvenile Xanthogranuloma
Langerhans Cell Histiocytosis
Observation
Bone and Bones
Drug Therapy
Lung
Liver
Therapeutics

Keywords

  • Histiocytic disorder
  • Juvenile xanthogranuloma
  • Liver
  • Neonatal

ASJC Scopus subject areas

  • Oncology

Cite this

Neonatal systemic juvenile xanthogranuloma with an ominous presentation and successful treatment. / Fan, Rong; Sun, Jihong.

In: Clinical Medicine Insights: Oncology, Vol. 5, 2011, p. 157-161.

Research output: Contribution to journalArticle

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