Neonatal systemic juvenile xanthogranuloma with an ominous presentation and successful treatment

Rong Fan, Jihong Sun

Research output: Contribution to journalReview article

12 Scopus citations

Abstract

This case report originated from a case of neonatal multisystemic juvenile xanthogranuloma (JXG). The patient presented with blue muffin rush, cervical mass, bone destruction, lung nodule, hepatosplenomegaly, and coagulopathy and was successfully treated with Langerhans cell histiocytosis (LCH) based chemotherapy treatment. Similar cases in literature were reviewed and it seems that JXG, a relatively benign entity, when presented in its systemic form with liver involvement, could have an aggressive course and portend quite poor prognosis. Challenges and special consideration of the diagnosis, treatment, and future case observation are discussed.

Original languageEnglish (US)
Pages (from-to)157-161
Number of pages5
JournalClinical Medicine Insights: Oncology
Volume5
DOIs
StatePublished - Jan 1 2011

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Keywords

  • Histiocytic disorder
  • Juvenile xanthogranuloma
  • Liver
  • Neonatal

ASJC Scopus subject areas

  • Oncology

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