Nephrogenic adenoma in the augmented bladder

Ethan I. Franke, Rosalia Misseri, Mark P. Cain, Martin Kaefer, Kirstan K. Meldrum, Rong Fan, Richard C. Rink

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Purpose: Nephrogenic adenoma is an uncommon, benign urothelial lesion. Risk factors for nephrogenic adenoma include trauma, chronic inflammation, immunosuppression and radiation. We characterized nephrogenic adenoma in the pediatric augmented bladder. Materials and Methods: We reviewed the records of patients diagnosed with nephrogenic adenoma from January 2000 to March 2010. Those with prior bladder augmentation were studied further. Data were retrospectively obtained on pathological characteristics, cystoscopic findings, recurrence patterns and presentation. Results: Ten patients with ileal bladder augmentation and nephrogenic adenoma were identified. The underlying pathological condition was myelodysplasia in 7 patients, sacral agenesis in 2 and bladder exstrophy in 1. Concomitant procedures were a continent channel in 9 patients, ureteroneocystostomy in 5 and bladder neck reconstruction in 7. Mean time to the discovery of nephrogenic adenoma was 9.2 years. During that time a total of 221 surveillance cystoscopies were performed in patients with bladder augmentation. The diagnosis was made by surveillance cystoscopy in 7 cases, at surgery for bladder stone in 2 and by cystoscopy for urinary incontinence in 1. Nephrogenic adenoma was identified along the floor in 5 cases, near the channel entrance in 3 and adjacent to the enteric anastomosis in 2. Six patients returned for surveillance with recurrence identified in 2. The longest recurrence free interval was 27 months. Conclusions: Nephrogenic adenoma is not uncommon in the augmented bladder and it is often asymptomatic. The lesions tend to develop at sites that may be prone to chronic catheterization injury. Recurrent lesions are not unusual.

Original languageEnglish
Pages (from-to)1586-1589
Number of pages4
JournalJournal of Urology
Volume186
Issue number4 SUPPL.
DOIs
StatePublished - Oct 2011

Fingerprint

Adenoma
Urinary Bladder
Cystoscopy
Recurrence
Bladder Exstrophy
Urinary Bladder Calculi
Wounds and Injuries
Urinary Incontinence
Catheterization
Immunosuppression
Radiation
Pediatrics
Inflammation

Keywords

  • adenoma
  • catheterization
  • cystitis
  • reconstructive surgical procedures
  • urinary bladder

ASJC Scopus subject areas

  • Urology

Cite this

Franke, E. I., Misseri, R., Cain, M. P., Kaefer, M., Meldrum, K. K., Fan, R., & Rink, R. C. (2011). Nephrogenic adenoma in the augmented bladder. Journal of Urology, 186(4 SUPPL.), 1586-1589. https://doi.org/10.1016/j.juro.2011.04.015

Nephrogenic adenoma in the augmented bladder. / Franke, Ethan I.; Misseri, Rosalia; Cain, Mark P.; Kaefer, Martin; Meldrum, Kirstan K.; Fan, Rong; Rink, Richard C.

In: Journal of Urology, Vol. 186, No. 4 SUPPL., 10.2011, p. 1586-1589.

Research output: Contribution to journalArticle

Franke, EI, Misseri, R, Cain, MP, Kaefer, M, Meldrum, KK, Fan, R & Rink, RC 2011, 'Nephrogenic adenoma in the augmented bladder', Journal of Urology, vol. 186, no. 4 SUPPL., pp. 1586-1589. https://doi.org/10.1016/j.juro.2011.04.015
Franke EI, Misseri R, Cain MP, Kaefer M, Meldrum KK, Fan R et al. Nephrogenic adenoma in the augmented bladder. Journal of Urology. 2011 Oct;186(4 SUPPL.):1586-1589. https://doi.org/10.1016/j.juro.2011.04.015
Franke, Ethan I. ; Misseri, Rosalia ; Cain, Mark P. ; Kaefer, Martin ; Meldrum, Kirstan K. ; Fan, Rong ; Rink, Richard C. / Nephrogenic adenoma in the augmented bladder. In: Journal of Urology. 2011 ; Vol. 186, No. 4 SUPPL. pp. 1586-1589.
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