Neural cyst of the ovary with central nervous system microvasculature

F. FOGT, Alexander Vortmeyer, G. AHN, U. DE GIROLAMI, R. B. HUNT, T. DALY, M. LODA

Research output: Contribution to journalArticle

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Abstract

A case of a monodermal teratoma of the ovary composed solely of mature neuroglial elements is described. The cyst lining comprised ependymal cells surrounded by white matter which itself was resting on mesothelial cells. Astrocytes, oligodendrocytes, microglia and neurofilament‐positive fibres were seen, but no neuron cell bodies were present. Immunohistochemical stains showed positivity for glial fibrillary acidic protein in ependymal, subependymal and the white matter regions while S‐100 protein positivity was restricted to the white matter. Vessels within neuroectodermal tissue, but not those within the mesodermal tissue, stained positively for anti‐glucose transporter protein, a marker shown to be present in vessels with barrier functions. We conclude that this is a rare case of monodermal teratoma consisting of purely mature brain tissue with a microvasculature exhibiting blood–brain barrier characteristics.

Original languageEnglish (US)
Pages (from-to)477-480
Number of pages4
JournalHistopathology
Volume24
Issue number5
DOIs
StatePublished - Jan 1 1994
Externally publishedYes

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Microvessels
Cysts
Ovary
Central Nervous System
Teratoma
S100 Proteins
Glial Fibrillary Acidic Protein
Oligodendroglia
Microglia
Astrocytes
Coloring Agents
Neurons
Brain
White Matter
Proteins

Keywords

  • erythrocyte glucose transport protein
  • immunohistochemistry
  • neurogenic cyst

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

Cite this

FOGT, F., Vortmeyer, A., AHN, G., GIROLAMI, U. DE., HUNT, R. B., DALY, T., & LODA, M. (1994). Neural cyst of the ovary with central nervous system microvasculature. Histopathology, 24(5), 477-480. https://doi.org/10.1111/j.1365-2559.1994.tb00558.x

Neural cyst of the ovary with central nervous system microvasculature. / FOGT, F.; Vortmeyer, Alexander; AHN, G.; GIROLAMI, U. DE; HUNT, R. B.; DALY, T.; LODA, M.

In: Histopathology, Vol. 24, No. 5, 01.01.1994, p. 477-480.

Research output: Contribution to journalArticle

FOGT, F, Vortmeyer, A, AHN, G, GIROLAMI, UDE, HUNT, RB, DALY, T & LODA, M 1994, 'Neural cyst of the ovary with central nervous system microvasculature', Histopathology, vol. 24, no. 5, pp. 477-480. https://doi.org/10.1111/j.1365-2559.1994.tb00558.x
FOGT, F. ; Vortmeyer, Alexander ; AHN, G. ; GIROLAMI, U. DE ; HUNT, R. B. ; DALY, T. ; LODA, M. / Neural cyst of the ovary with central nervous system microvasculature. In: Histopathology. 1994 ; Vol. 24, No. 5. pp. 477-480.
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