Neuroblastoma in the first year of life: clinical and biologic factors influencing outcome.

J. L. Grosfeld, F. J. Rescorla, K. W. West, J. Goldman

Research output: Contribution to journalReview article

31 Scopus citations

Abstract

The survival for infants less than 1 year of age with neuroblastoma is twice that of older children. This report describes 70 babies with neuroblastoma who experienced an 84% survival. Survival was 100% for stages I, II, and III, 81% for stage IV-S, and 50% for stage IV. Most survivors had favorable biologic characteristics including spontaneous regression, favorable Shimada histology, normal first chromosome, aneuploid tumors, absent or low N-myc oncogene expression, and normal serum ferritin levels.

Original languageEnglish (US)
Pages (from-to)37-46
Number of pages10
JournalSeminars in pediatric surgery
Volume2
Issue number1
StatePublished - Feb 1 1993

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

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