Neuroblastoma in the first year of life

clinical and biologic factors influencing outcome.

J. L. Grosfeld, Frederick Rescorla, K. W. West, J. Goldman

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The survival for infants less than 1 year of age with neuroblastoma is twice that of older children. This report describes 70 babies with neuroblastoma who experienced an 84% survival. Survival was 100% for stages I, II, and III, 81% for stage IV-S, and 50% for stage IV. Most survivors had favorable biologic characteristics including spontaneous regression, favorable Shimada histology, normal first chromosome, aneuploid tumors, absent or low N-myc oncogene expression, and normal serum ferritin levels.

Original languageEnglish
Pages (from-to)37-46
Number of pages10
JournalSeminars in Pediatric Surgery
Volume2
Issue number1
StatePublished - Feb 1993

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Biological Factors
Neuroblastoma
myc Genes
Aneuploidy
Ferritins
Histology
Chromosomes
Serum
Neoplasms

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Neuroblastoma in the first year of life : clinical and biologic factors influencing outcome. / Grosfeld, J. L.; Rescorla, Frederick; West, K. W.; Goldman, J.

In: Seminars in Pediatric Surgery, Vol. 2, No. 1, 02.1993, p. 37-46.

Research output: Contribution to journalArticle

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