Neuroimaging findings in mild traumatic brain injury

Thomas W. McAllister, Molly B. Sparling, Laura A. Flashman, Andrew Saykin

Research output: Contribution to journalArticle

101 Citations (Scopus)

Abstract

The role of neuroimaging in the diagnosis and management of mild traumatic brain injury (TBI) is evolving. In general, the structural imaging techniques play a role in acute diagnosis and management, while the functional imaging techniques show promise for clarification of pathophysiology, symptom genesis, and mechanisms of recovery. A wide array of neuropathological processes are involved in mild TBI including changes in bone (e.g., a skull fracture), tissue density and water content (edema), blood flow, white matter integrity and pathway connectivity (diffuse axonal injury), and subtle changes in the neuronal and extracellular biochemical milieu. No single imaging technique is capable of addressing all these processes. It is, therefore, important to be aware of the advantages and limitations of the various available imaging modalities. This paper selectively reviews the pertinent literature on the structural and functional imaging in mild TBI.

Original languageEnglish (US)
Pages (from-to)775-791
Number of pages17
JournalJournal of Clinical and Experimental Neuropsychology
Volume23
Issue number6
StatePublished - 2001
Externally publishedYes

Fingerprint

Brain Concussion
Neuroimaging
Diffuse Axonal Injury
Skull Fractures
Edema
Bone and Bones
Water

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Psychology(all)
  • Clinical Psychology

Cite this

McAllister, T. W., Sparling, M. B., Flashman, L. A., & Saykin, A. (2001). Neuroimaging findings in mild traumatic brain injury. Journal of Clinical and Experimental Neuropsychology, 23(6), 775-791.

Neuroimaging findings in mild traumatic brain injury. / McAllister, Thomas W.; Sparling, Molly B.; Flashman, Laura A.; Saykin, Andrew.

In: Journal of Clinical and Experimental Neuropsychology, Vol. 23, No. 6, 2001, p. 775-791.

Research output: Contribution to journalArticle

McAllister, TW, Sparling, MB, Flashman, LA & Saykin, A 2001, 'Neuroimaging findings in mild traumatic brain injury', Journal of Clinical and Experimental Neuropsychology, vol. 23, no. 6, pp. 775-791.
McAllister, Thomas W. ; Sparling, Molly B. ; Flashman, Laura A. ; Saykin, Andrew. / Neuroimaging findings in mild traumatic brain injury. In: Journal of Clinical and Experimental Neuropsychology. 2001 ; Vol. 23, No. 6. pp. 775-791.
@article{7e4936f2e7b646b785ea8315817f6773,
title = "Neuroimaging findings in mild traumatic brain injury",
abstract = "The role of neuroimaging in the diagnosis and management of mild traumatic brain injury (TBI) is evolving. In general, the structural imaging techniques play a role in acute diagnosis and management, while the functional imaging techniques show promise for clarification of pathophysiology, symptom genesis, and mechanisms of recovery. A wide array of neuropathological processes are involved in mild TBI including changes in bone (e.g., a skull fracture), tissue density and water content (edema), blood flow, white matter integrity and pathway connectivity (diffuse axonal injury), and subtle changes in the neuronal and extracellular biochemical milieu. No single imaging technique is capable of addressing all these processes. It is, therefore, important to be aware of the advantages and limitations of the various available imaging modalities. This paper selectively reviews the pertinent literature on the structural and functional imaging in mild TBI.",
author = "McAllister, {Thomas W.} and Sparling, {Molly B.} and Flashman, {Laura A.} and Andrew Saykin",
year = "2001",
language = "English (US)",
volume = "23",
pages = "775--791",
journal = "Journal of Clinical and Experimental Neuropsychology",
issn = "1380-3395",
publisher = "Psychology Press Ltd",
number = "6",

}

TY - JOUR

T1 - Neuroimaging findings in mild traumatic brain injury

AU - McAllister, Thomas W.

AU - Sparling, Molly B.

AU - Flashman, Laura A.

AU - Saykin, Andrew

PY - 2001

Y1 - 2001

N2 - The role of neuroimaging in the diagnosis and management of mild traumatic brain injury (TBI) is evolving. In general, the structural imaging techniques play a role in acute diagnosis and management, while the functional imaging techniques show promise for clarification of pathophysiology, symptom genesis, and mechanisms of recovery. A wide array of neuropathological processes are involved in mild TBI including changes in bone (e.g., a skull fracture), tissue density and water content (edema), blood flow, white matter integrity and pathway connectivity (diffuse axonal injury), and subtle changes in the neuronal and extracellular biochemical milieu. No single imaging technique is capable of addressing all these processes. It is, therefore, important to be aware of the advantages and limitations of the various available imaging modalities. This paper selectively reviews the pertinent literature on the structural and functional imaging in mild TBI.

AB - The role of neuroimaging in the diagnosis and management of mild traumatic brain injury (TBI) is evolving. In general, the structural imaging techniques play a role in acute diagnosis and management, while the functional imaging techniques show promise for clarification of pathophysiology, symptom genesis, and mechanisms of recovery. A wide array of neuropathological processes are involved in mild TBI including changes in bone (e.g., a skull fracture), tissue density and water content (edema), blood flow, white matter integrity and pathway connectivity (diffuse axonal injury), and subtle changes in the neuronal and extracellular biochemical milieu. No single imaging technique is capable of addressing all these processes. It is, therefore, important to be aware of the advantages and limitations of the various available imaging modalities. This paper selectively reviews the pertinent literature on the structural and functional imaging in mild TBI.

UR - http://www.scopus.com/inward/record.url?scp=0035751964&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035751964&partnerID=8YFLogxK

M3 - Article

C2 - 11910544

AN - SCOPUS:0035751964

VL - 23

SP - 775

EP - 791

JO - Journal of Clinical and Experimental Neuropsychology

JF - Journal of Clinical and Experimental Neuropsychology

SN - 1380-3395

IS - 6

ER -