Neuronal antinuclear antibodies in a patient with lambert-eaton myasthenic syndrome and small-cell lung carcinoma

Edward Dropcho, Constance Stanton, Shin J. Oh

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

A patient with small-cell lung carcinoma and the Lambert-Eaton myasthenic syndrome had circulating neuronal antinuclear antibodies. Serum stained the nuclei of all neurons in sections of human brain and identified a closely spaced group of 33–39 kDa proteins in immunoblots of human neuronal nuclei, These autoantibodies are indistinguishable from those recently identified in patients with paraneoplastic subacute sensory neuronopathy.

Original languageEnglish (US)
Pages (from-to)249-251
Number of pages3
JournalNeurology
Volume39
Issue number2
StatePublished - 1989
Externally publishedYes

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Lambert-Eaton Myasthenic Syndrome
Antinuclear Antibodies
Small Cell Lung Carcinoma
Autoantibodies
Neurons
Brain
Serum
Proteins
Cells
Syndrome
Nucleus

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Neuronal antinuclear antibodies in a patient with lambert-eaton myasthenic syndrome and small-cell lung carcinoma. / Dropcho, Edward; Stanton, Constance; Oh, Shin J.

In: Neurology, Vol. 39, No. 2, 1989, p. 249-251.

Research output: Contribution to journalArticle

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