Neuronal antinuclear antibodies in a patient with lambert-eaton myasthenic syndrome and small-cell lung carcinoma

Edward J. Dropcho, Constance Stanton, Shin J. Oh

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Abstract

A patient with small-cell lung carcinoma and the Lambert-Eaton myasthenic syndrome had circulating neuronal antinuclear antibodies. Serum stained the nuclei of all neurons in sections of human brain and identified a closely spaced group of 33–39 kDa proteins in immunoblots of human neuronal nuclei, These autoantibodies are indistinguishable from those recently identified in patients with paraneoplastic subacute sensory neuronopathy.

Original languageEnglish (US)
Pages (from-to)249-251
Number of pages3
JournalNeurology
Volume39
Issue number2
StatePublished - Feb 1989

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ASJC Scopus subject areas

  • Clinical Neurology

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