A patient with small-cell lung carcinoma and the Lambert-Eaton myasthenic syndrome had circulating neuronal antinuclear antibodies. Serum stained the nuclei of all neurons in sections of human brain and identified a closely spaced group of 33–39 kDa proteins in immunoblots of human neuronal nuclei, These autoantibodies are indistinguishable from those recently identified in patients with paraneoplastic subacute sensory neuronopathy.
|Original language||English (US)|
|Number of pages||3|
|State||Published - Feb 1989|
ASJC Scopus subject areas
- Clinical Neurology