Neuropeptide Y immunoreactivity in human cerebrospinal fluid

Wade H. Berrettini, John Nurnberger, Debora A. Dimaggio

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Neuropeptide Y (NPY) immunoreactivity has been determined in human cerebrospinal fluid (CSF). High pressure liquid chromatography revealed that the NPY immunoreactivity co-eluted with authentic NPY. The range of NPY levels was 108±18 pg/ml (mean±S.D.) in a group of 28 normal subjects. In five additional subjects NPY immunoreactivity was measured in 4 sequential 8 ml aliquots of CSF to determine whether a rostro-caudal gradient was present. No significant differences in NPY levels were detected between any of the 4 aliquots.

Original languageEnglish (US)
Pages (from-to)455-458
Number of pages4
JournalPeptides
Volume7
Issue number3
DOIs
StatePublished - 1986
Externally publishedYes

Fingerprint

Cerebrospinal fluid
Neuropeptide Y
Cerebrospinal Fluid
High pressure liquid chromatography
High Pressure Liquid Chromatography

Keywords

  • Human cerebrospinal fluid (CSF)
  • Human studies
  • Neuropeptide Y immunoreactivity (NPY)

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology
  • Physiology
  • Cellular and Molecular Neuroscience

Cite this

Neuropeptide Y immunoreactivity in human cerebrospinal fluid. / Berrettini, Wade H.; Nurnberger, John; Dimaggio, Debora A.

In: Peptides, Vol. 7, No. 3, 1986, p. 455-458.

Research output: Contribution to journalArticle

Berrettini, Wade H. ; Nurnberger, John ; Dimaggio, Debora A. / Neuropeptide Y immunoreactivity in human cerebrospinal fluid. In: Peptides. 1986 ; Vol. 7, No. 3. pp. 455-458.
@article{5686a9ab165e4ef0a2b22cd463efdd91,
title = "Neuropeptide Y immunoreactivity in human cerebrospinal fluid",
abstract = "Neuropeptide Y (NPY) immunoreactivity has been determined in human cerebrospinal fluid (CSF). High pressure liquid chromatography revealed that the NPY immunoreactivity co-eluted with authentic NPY. The range of NPY levels was 108±18 pg/ml (mean±S.D.) in a group of 28 normal subjects. In five additional subjects NPY immunoreactivity was measured in 4 sequential 8 ml aliquots of CSF to determine whether a rostro-caudal gradient was present. No significant differences in NPY levels were detected between any of the 4 aliquots.",
keywords = "Human cerebrospinal fluid (CSF), Human studies, Neuropeptide Y immunoreactivity (NPY)",
author = "Berrettini, {Wade H.} and John Nurnberger and Dimaggio, {Debora A.}",
year = "1986",
doi = "10.1016/0196-9781(86)90014-8",
language = "English (US)",
volume = "7",
pages = "455--458",
journal = "Peptides",
issn = "0196-9781",
publisher = "Elsevier Inc.",
number = "3",

}

TY - JOUR

T1 - Neuropeptide Y immunoreactivity in human cerebrospinal fluid

AU - Berrettini, Wade H.

AU - Nurnberger, John

AU - Dimaggio, Debora A.

PY - 1986

Y1 - 1986

N2 - Neuropeptide Y (NPY) immunoreactivity has been determined in human cerebrospinal fluid (CSF). High pressure liquid chromatography revealed that the NPY immunoreactivity co-eluted with authentic NPY. The range of NPY levels was 108±18 pg/ml (mean±S.D.) in a group of 28 normal subjects. In five additional subjects NPY immunoreactivity was measured in 4 sequential 8 ml aliquots of CSF to determine whether a rostro-caudal gradient was present. No significant differences in NPY levels were detected between any of the 4 aliquots.

AB - Neuropeptide Y (NPY) immunoreactivity has been determined in human cerebrospinal fluid (CSF). High pressure liquid chromatography revealed that the NPY immunoreactivity co-eluted with authentic NPY. The range of NPY levels was 108±18 pg/ml (mean±S.D.) in a group of 28 normal subjects. In five additional subjects NPY immunoreactivity was measured in 4 sequential 8 ml aliquots of CSF to determine whether a rostro-caudal gradient was present. No significant differences in NPY levels were detected between any of the 4 aliquots.

KW - Human cerebrospinal fluid (CSF)

KW - Human studies

KW - Neuropeptide Y immunoreactivity (NPY)

UR - http://www.scopus.com/inward/record.url?scp=0022448473&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022448473&partnerID=8YFLogxK

U2 - 10.1016/0196-9781(86)90014-8

DO - 10.1016/0196-9781(86)90014-8

M3 - Article

VL - 7

SP - 455

EP - 458

JO - Peptides

JF - Peptides

SN - 0196-9781

IS - 3

ER -