Neuropeptide Y immunoreactivity in human cerebrospinal fluid

Wade H. Berrettini, John I. Nurnberger, Debora A. Dimaggio

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

Neuropeptide Y (NPY) immunoreactivity has been determined in human cerebrospinal fluid (CSF). High pressure liquid chromatography revealed that the NPY immunoreactivity co-eluted with authentic NPY. The range of NPY levels was 108±18 pg/ml (mean±S.D.) in a group of 28 normal subjects. In five additional subjects NPY immunoreactivity was measured in 4 sequential 8 ml aliquots of CSF to determine whether a rostro-caudal gradient was present. No significant differences in NPY levels were detected between any of the 4 aliquots.

Original languageEnglish (US)
Pages (from-to)455-458
Number of pages4
JournalPeptides
Volume7
Issue number3
DOIs
StatePublished - Jan 1 1986
Externally publishedYes

Keywords

  • Human cerebrospinal fluid (CSF)
  • Human studies
  • Neuropeptide Y immunoreactivity (NPY)

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Endocrinology
  • Cellular and Molecular Neuroscience

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