Neuropeptides as biologial system integrators - Mini review

Gabi N. Waite, Roy W. Geib, Michael W. King

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

This paper provides a review on the emerging role of neuropeptides for body systems integration. Neuropeptides are small protein-like substances that are released into the synaptic space and/or the blood, hence, acting as neurotransmitters and neurohormones. Classically, their role has been viewed as integrating the central nervous system and the endocrine system. More recently, however, there is an emerging understanding that neuropeptides integrate many more body systems into a larger cohesive body response that involves basic body functions, behavior, and mind. One indication is the discovery that neurohormones are also produced by many peripheral tissues and that non-neuronal peptides are released by neurons as well. Examples from the gastrointestinal and the immune system are presented. With the emerging role of neuropeptides for systems integration, immense opportunities arise for their use as pharmacological agents and biomarkers in the diagnosis and treatment of countless disorders such as chronic inflammatory diseases and obesity.

Original languageEnglish (US)
Title of host publication51st Annual Rocky Mountain Bioengineering Symposium, RMBS 2014 and 51st International ISA Biomedical Sciences Instrumentation Symposium 2014
PublisherISA - Instrumentation, Systems, and Automation Society
Pages1-11
Number of pages11
ISBN (Print)9781632663917
StatePublished - Jan 1 2014
Event51st Annual Rocky Mountain Bioengineering Symposium, RMBS 2014 and 51st International ISA Biomedical Sciences Instrumentation Symposium 2014 - Denver, CO, United States
Duration: Apr 4 2014Apr 6 2014

Publication series

Name51st Annual Rocky Mountain Bioengineering Symposium, RMBS 2014 and 51st International ISA Biomedical Sciences Instrumentation Symposium 2014

Other

Other51st Annual Rocky Mountain Bioengineering Symposium, RMBS 2014 and 51st International ISA Biomedical Sciences Instrumentation Symposium 2014
CountryUnited States
CityDenver, CO
Period4/4/144/6/14

Keywords

  • Chronic disease
  • Cytokine
  • Gastrointestinal system
  • Immune system
  • Inflammation
  • Integration
  • Neurohormone

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering
  • Instrumentation

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  • Cite this

    Waite, G. N., Geib, R. W., & King, M. W. (2014). Neuropeptides as biologial system integrators - Mini review. In 51st Annual Rocky Mountain Bioengineering Symposium, RMBS 2014 and 51st International ISA Biomedical Sciences Instrumentation Symposium 2014 (pp. 1-11). (51st Annual Rocky Mountain Bioengineering Symposium, RMBS 2014 and 51st International ISA Biomedical Sciences Instrumentation Symposium 2014). ISA - Instrumentation, Systems, and Automation Society.