Neuropeptides in human cerebrospinal fluid

Wade H. Berrettini, John Nurnberger, Philip W. Gold, Michel Chretien, George P. Chrousos, J. S D Chan, Lynn R. Goldin, Elliot S. Gershon

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Ten neuropeptides were measured by RIA in human cerebrospinal fluid obtained from 30 normal volunteers. The levels of seven peptides (corticotropin releasing factor, adrenocorticotropin, vasoactive intestinal peptide, somatostatin, beta-endorphin, beta-lipotropin, and the N-terminal fragment of proopiomelanocortin) were highly, positively correlated with one another. This result is consistent with the hypothesis that cerebrospinal fluid levels of these seven peptides are a function of some common regulatory factor, such as shared release into the cerebrospinal fluid.

Original languageEnglish (US)
Pages (from-to)1265-1270
Number of pages6
JournalLife Sciences
Volume37
Issue number13
DOIs
StatePublished - Sep 30 1985
Externally publishedYes

Fingerprint

Cerebrospinal fluid
Neuropeptides
Cerebrospinal Fluid
beta-Lipotropin
Pro-Opiomelanocortin
Peptides
beta-Endorphin
Corticotropin-Releasing Hormone
Vasoactive Intestinal Peptide
Somatostatin
Adrenocorticotropic Hormone
Healthy Volunteers

ASJC Scopus subject areas

  • Pharmacology

Cite this

Berrettini, W. H., Nurnberger, J., Gold, P. W., Chretien, M., Chrousos, G. P., Chan, J. S. D., ... Gershon, E. S. (1985). Neuropeptides in human cerebrospinal fluid. Life Sciences, 37(13), 1265-1270. https://doi.org/10.1016/0024-3205(85)90139-0

Neuropeptides in human cerebrospinal fluid. / Berrettini, Wade H.; Nurnberger, John; Gold, Philip W.; Chretien, Michel; Chrousos, George P.; Chan, J. S D; Goldin, Lynn R.; Gershon, Elliot S.

In: Life Sciences, Vol. 37, No. 13, 30.09.1985, p. 1265-1270.

Research output: Contribution to journalArticle

Berrettini, WH, Nurnberger, J, Gold, PW, Chretien, M, Chrousos, GP, Chan, JSD, Goldin, LR & Gershon, ES 1985, 'Neuropeptides in human cerebrospinal fluid', Life Sciences, vol. 37, no. 13, pp. 1265-1270. https://doi.org/10.1016/0024-3205(85)90139-0
Berrettini WH, Nurnberger J, Gold PW, Chretien M, Chrousos GP, Chan JSD et al. Neuropeptides in human cerebrospinal fluid. Life Sciences. 1985 Sep 30;37(13):1265-1270. https://doi.org/10.1016/0024-3205(85)90139-0
Berrettini, Wade H. ; Nurnberger, John ; Gold, Philip W. ; Chretien, Michel ; Chrousos, George P. ; Chan, J. S D ; Goldin, Lynn R. ; Gershon, Elliot S. / Neuropeptides in human cerebrospinal fluid. In: Life Sciences. 1985 ; Vol. 37, No. 13. pp. 1265-1270.
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