Neurotoxicity of Radiation Therapy

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

Direct or incidental exposure of the nervous system to therapeutic irradiation carries the risk of symptomatic neurologic injury. Central nervous system toxicity from radiation includes focal cerebral necrosis, neurocognitive deficits, and less commonly cerebrovascular disease, myelopathy, or the occurrence of a radiation-induced neoplasm. Brachial or lumbosacral plexopathy are the most common syndromes of radiation toxicity affecting the peripheral nervous system. This article focuses on the clinical features, diagnosis, and management options for patients with radiation neurotoxicity.

Original languageEnglish
Pages (from-to)217-234
Number of pages18
JournalNeurologic Clinics
Volume28
Issue number1
DOIs
StatePublished - Feb 2010

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Radiotherapy
Radiation-Induced Neoplasms
Radiation
Nervous System Trauma
Cerebrovascular Disorders
Radiation Injuries
Spinal Cord Diseases
Peripheral Nervous System
Nervous System
Arm
Necrosis
Central Nervous System
Therapeutics

Keywords

  • Brachial plexopathy
  • Brain neoplasms
  • Lumbosacral plexopathy
  • Myelopathy
  • Radiation adverse effects

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Neurotoxicity of Radiation Therapy. / Dropcho, Edward.

In: Neurologic Clinics, Vol. 28, No. 1, 02.2010, p. 217-234.

Research output: Contribution to journalArticle

Dropcho, Edward. / Neurotoxicity of Radiation Therapy. In: Neurologic Clinics. 2010 ; Vol. 28, No. 1. pp. 217-234.
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