No association between vitamin D intake and incident psoriasis among US women

Joseph F. Merola, Jiali Han, Tricia Li, Abrar A. Qureshi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We investigated the association between dietary, supplementary and total vitamin D intake and incident psoriasis in women. A prospective study was performed of 70,437 US female nurses aged 47-74 enrolled in the Nurses' Health Study who did not have psoriasis at baseline in 1994 and who completed semi-quantitative food frequency questionnaires in 1994, 1998, 2002 and 2006. The incidence of clinician-diagnosed psoriasis was ascertained and validated by self-reported questionnaires. 502 confirmed incident psoriasis cases were documented during 973,057 person-years of follow-up from 1994 June to 2008 June. Association between vitamin D intake and incident psoriasis was assessed using multivariable-adjusted cox regression analysis. After adjusting for age, smoking, body mass index, calorie intake, UV flux, exercise and alcohol use, there was no significant association between vitamin D intake (dietary, supplementary and total vitamin D) and the risk of incident psoriasis. Compared with women whose dietary vitamin D intake was <100 IU/day, multivariate relative risks for psoriasis was 1.13 (95 % CI 0.66-1.92) for ≥400 IU/day (P trend = 0.88). The multivariate relative risk for women who took supplementary vitamin D ≥400 IU/day was 1.18 (95 % CI 0.88-1.58) compared with women who did not take supplementary vitamin D. The multivariate risk for women who had total vitamin D intake of 300-399 IU/day was no different than at higher and lower doses of vitamin D intake. Our study does not support preventive roles of dietary or supplemental vitamin D intake for incident psoriasis.

Original languageEnglish (US)
Pages (from-to)305-307
Number of pages3
JournalArchives of Dermatological Research
Volume306
Issue number3
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

Fingerprint

Psoriasis
Vitamin D
Nurses
Body Mass Index
Smoking
Regression Analysis
Alcohols
Prospective Studies
Exercise
Food
Incidence
Health

Keywords

  • Epidemiology
  • Psoriasis
  • Vitamin D

ASJC Scopus subject areas

  • Dermatology

Cite this

No association between vitamin D intake and incident psoriasis among US women. / Merola, Joseph F.; Han, Jiali; Li, Tricia; Qureshi, Abrar A.

In: Archives of Dermatological Research, Vol. 306, No. 3, 01.01.2014, p. 305-307.

Research output: Contribution to journalArticle

Merola, Joseph F. ; Han, Jiali ; Li, Tricia ; Qureshi, Abrar A. / No association between vitamin D intake and incident psoriasis among US women. In: Archives of Dermatological Research. 2014 ; Vol. 306, No. 3. pp. 305-307.
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