Nodular Leydig cell hyperplasia in a boy with familial male-limited precocious puberty

Ellen Werber Leschek, Wai Yee Chan, David A. Diamond, Martin Kaefer, Janet Jones, Kevin M. Barnes, Gordon B. Cutler

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

In boys with familial male-limited precocious puberty, an activating mutation of the luteinizing hormone receptor causes Leydig cell hyperplasia, resulting in excess testosterone production. There are no reports of Leydig cell masses in boys with familial male-limited precocious puberty. We describe a 10-year-old boy with familial male-limited precocious puberty who developed Leydig cell nodules.

Original languageEnglish
Pages (from-to)949-951
Number of pages3
JournalJournal of Pediatrics
Volume138
Issue number6
DOIs
StatePublished - 2001

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Leydig Cells
Hyperplasia
LH Receptors
Testosterone
Mutation
Familial Testotoxicosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Leschek, E. W., Chan, W. Y., Diamond, D. A., Kaefer, M., Jones, J., Barnes, K. M., & Cutler, G. B. (2001). Nodular Leydig cell hyperplasia in a boy with familial male-limited precocious puberty. Journal of Pediatrics, 138(6), 949-951. https://doi.org/10.1067/mpd.2001.114477

Nodular Leydig cell hyperplasia in a boy with familial male-limited precocious puberty. / Leschek, Ellen Werber; Chan, Wai Yee; Diamond, David A.; Kaefer, Martin; Jones, Janet; Barnes, Kevin M.; Cutler, Gordon B.

In: Journal of Pediatrics, Vol. 138, No. 6, 2001, p. 949-951.

Research output: Contribution to journalArticle

Leschek, EW, Chan, WY, Diamond, DA, Kaefer, M, Jones, J, Barnes, KM & Cutler, GB 2001, 'Nodular Leydig cell hyperplasia in a boy with familial male-limited precocious puberty', Journal of Pediatrics, vol. 138, no. 6, pp. 949-951. https://doi.org/10.1067/mpd.2001.114477
Leschek, Ellen Werber ; Chan, Wai Yee ; Diamond, David A. ; Kaefer, Martin ; Jones, Janet ; Barnes, Kevin M. ; Cutler, Gordon B. / Nodular Leydig cell hyperplasia in a boy with familial male-limited precocious puberty. In: Journal of Pediatrics. 2001 ; Vol. 138, No. 6. pp. 949-951.
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