Nodular Leydig cell hyperplasia in a boy with familial male-limited precocious puberty

Ellen Werber Leschek, Wai Yee Chan, David A. Diamond, Martin Kaefer, Janet Jones, Kevin M. Barnes, Gordon B. Cutler

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

In boys with familial male-limited precocious puberty, an activating mutation of the luteinizing hormone receptor causes Leydig cell hyperplasia, resulting in excess testosterone production. There are no reports of Leydig cell masses in boys with familial male-limited precocious puberty. We describe a 10-year-old boy with familial male-limited precocious puberty who developed Leydig cell nodules.

Original languageEnglish (US)
Pages (from-to)949-951
Number of pages3
JournalJournal of Pediatrics
Volume138
Issue number6
DOIs
StatePublished - 2001

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Leschek, E. W., Chan, W. Y., Diamond, D. A., Kaefer, M., Jones, J., Barnes, K. M., & Cutler, G. B. (2001). Nodular Leydig cell hyperplasia in a boy with familial male-limited precocious puberty. Journal of Pediatrics, 138(6), 949-951. https://doi.org/10.1067/mpd.2001.114477