Nomenclature of the finer branches of the biliary tree: Canals, ductules, and ductular reactions in human livers

Tania A. Roskams, Neil D. Theise, Charles Balabaud, Govind Bhagat, Prithi S. Bhathal, Paulette Bioulac-Sage, Elizabeth M. Brunt, James M. Crawford, Heather A. Crosby, Valeer Desmet, Milton J. Finegold, Stephen A. Geller, Annette S.H. Gouw, Prodromos Hytiroglou, A. S. Knisely, Masamichi Kojiro, Jay H. Lefkowitch, Yasuni Nakanuma, John K. Olynyk, Young Nyun ParkBernard Portmann, Romil Saxena, Peter J. Scheuer, Alastair J. Strain, Swan N. Thung, Ian R. Wanless, A. Brian West

Research output: Contribution to journalReview article

477 Scopus citations

Abstract

The work of liver stem cell biologists, largely carried out in rodent models, has now started to manifest in human investigations and applications. We can now recognize complex regenerative processes in tissue specimens that had only been suspected for decades, but we also struggle to describe what we see in human tissues in a way that takes into account the findings from the animal investigations, using a language derived from species not, in fact, so much like our own. This international group of liver pathologists and hepatologists, most of whom are actively engaged in both clinical work and scientific research, seeks to arrive at a consensus on nomenclature for normal human livers and human reactive lesions that can facilitate more rapid advancement of our field.

Original languageEnglish (US)
Pages (from-to)1739-1745
Number of pages7
JournalHepatology
Volume39
Issue number6
DOIs
StatePublished - Jun 1 2004

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ASJC Scopus subject areas

  • Hepatology

Cite this

Roskams, T. A., Theise, N. D., Balabaud, C., Bhagat, G., Bhathal, P. S., Bioulac-Sage, P., Brunt, E. M., Crawford, J. M., Crosby, H. A., Desmet, V., Finegold, M. J., Geller, S. A., Gouw, A. S. H., Hytiroglou, P., Knisely, A. S., Kojiro, M., Lefkowitch, J. H., Nakanuma, Y., Olynyk, J. K., ... West, A. B. (2004). Nomenclature of the finer branches of the biliary tree: Canals, ductules, and ductular reactions in human livers. Hepatology, 39(6), 1739-1745. https://doi.org/10.1002/hep.20130