Non-atherosclerotic fusiform cerebral aneurysms

J. Max Findlay, Chunhai Hao, Derek Emery

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Background: Fusiform cerebral aneurysms are dilatations of the entire circumference of a segment of cerebral artery, usually considered due to atherosclerosis in adults. They are relatively thick-walled and elongated, causing neural compression or ischemia when discovered. We have noted a subset of fusiform cerebral aneurysms that vary from this common description. Patients: Out of a series of 472 intracranial aneurysms treated over 11 years, 11 patients between the ages 16 and 67 years (mean age 37) were identified who had discrete fusiform aneurysms unassociated with generalized cerebral atherosclerosis, connective tissue disorder or inflammation. Three presented with hemorrhage, six with neural compression by the aneurysm and two were discovered incidentally. Results: Nine aneurysms were located in the posterior circulation, the other two in the intracranial carotid artery. Their mean length and width were 16.3 and 11 mm, respectively. Three aneurysms contained thrombus. The eight aneurysms that were exposed surgically were partly or substantially thin-walled with normal appearing parent arteries. Eight were treated with proximal occlusion and three were circumferentially "wrapped". Parent artery occlusion caused one death and one mild disability and the remaining patients made good recoveries (follow-up 0.5-10 years). Conclusions: There is a subset of cerebral aneurysms with discrete fusiform morphology, apparently unrelated to cerebral atherosclerosis or systemic connective tissue disease, thin-walled in part or whole, more common in the vertebrobasilar system, and possessing a risk of rupture. Treatments currently available include proximal occlusion or aneurysm "wrapping", different approaches than neck-clipping or endovascular coiling of side-wall saccular cerebral aneurysms that leave the parent artery intact.

Original languageEnglish (US)
Pages (from-to)41-48
Number of pages8
JournalCanadian Journal of Neurological Sciences
Volume29
Issue number1
DOIs
StatePublished - Jan 1 2002
Externally publishedYes

Fingerprint

Intracranial Aneurysm
Aneurysm
Intracranial Arteriosclerosis
Arteries
Connective Tissue Diseases
Cerebral Arteries
Carotid Arteries
Connective Tissue
Rupture
Dilatation
Atherosclerosis
Thrombosis
Neck
Ischemia
Hemorrhage
Inflammation

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Non-atherosclerotic fusiform cerebral aneurysms. / Findlay, J. Max; Hao, Chunhai; Emery, Derek.

In: Canadian Journal of Neurological Sciences, Vol. 29, No. 1, 01.01.2002, p. 41-48.

Research output: Contribution to journalArticle

Findlay, J. Max ; Hao, Chunhai ; Emery, Derek. / Non-atherosclerotic fusiform cerebral aneurysms. In: Canadian Journal of Neurological Sciences. 2002 ; Vol. 29, No. 1. pp. 41-48.
@article{ed0e7491780e44308c21bb99bb74c749,
title = "Non-atherosclerotic fusiform cerebral aneurysms",
abstract = "Background: Fusiform cerebral aneurysms are dilatations of the entire circumference of a segment of cerebral artery, usually considered due to atherosclerosis in adults. They are relatively thick-walled and elongated, causing neural compression or ischemia when discovered. We have noted a subset of fusiform cerebral aneurysms that vary from this common description. Patients: Out of a series of 472 intracranial aneurysms treated over 11 years, 11 patients between the ages 16 and 67 years (mean age 37) were identified who had discrete fusiform aneurysms unassociated with generalized cerebral atherosclerosis, connective tissue disorder or inflammation. Three presented with hemorrhage, six with neural compression by the aneurysm and two were discovered incidentally. Results: Nine aneurysms were located in the posterior circulation, the other two in the intracranial carotid artery. Their mean length and width were 16.3 and 11 mm, respectively. Three aneurysms contained thrombus. The eight aneurysms that were exposed surgically were partly or substantially thin-walled with normal appearing parent arteries. Eight were treated with proximal occlusion and three were circumferentially {"}wrapped{"}. Parent artery occlusion caused one death and one mild disability and the remaining patients made good recoveries (follow-up 0.5-10 years). Conclusions: There is a subset of cerebral aneurysms with discrete fusiform morphology, apparently unrelated to cerebral atherosclerosis or systemic connective tissue disease, thin-walled in part or whole, more common in the vertebrobasilar system, and possessing a risk of rupture. Treatments currently available include proximal occlusion or aneurysm {"}wrapping{"}, different approaches than neck-clipping or endovascular coiling of side-wall saccular cerebral aneurysms that leave the parent artery intact.",
author = "Findlay, {J. Max} and Chunhai Hao and Derek Emery",
year = "2002",
month = "1",
day = "1",
doi = "10.1017/S0317167100001700",
language = "English (US)",
volume = "29",
pages = "41--48",
journal = "Canadian Journal of Neurological Sciences",
issn = "0317-1671",
publisher = "Canadian Journal of Neurological Sciences",
number = "1",

}

TY - JOUR

T1 - Non-atherosclerotic fusiform cerebral aneurysms

AU - Findlay, J. Max

AU - Hao, Chunhai

AU - Emery, Derek

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Background: Fusiform cerebral aneurysms are dilatations of the entire circumference of a segment of cerebral artery, usually considered due to atherosclerosis in adults. They are relatively thick-walled and elongated, causing neural compression or ischemia when discovered. We have noted a subset of fusiform cerebral aneurysms that vary from this common description. Patients: Out of a series of 472 intracranial aneurysms treated over 11 years, 11 patients between the ages 16 and 67 years (mean age 37) were identified who had discrete fusiform aneurysms unassociated with generalized cerebral atherosclerosis, connective tissue disorder or inflammation. Three presented with hemorrhage, six with neural compression by the aneurysm and two were discovered incidentally. Results: Nine aneurysms were located in the posterior circulation, the other two in the intracranial carotid artery. Their mean length and width were 16.3 and 11 mm, respectively. Three aneurysms contained thrombus. The eight aneurysms that were exposed surgically were partly or substantially thin-walled with normal appearing parent arteries. Eight were treated with proximal occlusion and three were circumferentially "wrapped". Parent artery occlusion caused one death and one mild disability and the remaining patients made good recoveries (follow-up 0.5-10 years). Conclusions: There is a subset of cerebral aneurysms with discrete fusiform morphology, apparently unrelated to cerebral atherosclerosis or systemic connective tissue disease, thin-walled in part or whole, more common in the vertebrobasilar system, and possessing a risk of rupture. Treatments currently available include proximal occlusion or aneurysm "wrapping", different approaches than neck-clipping or endovascular coiling of side-wall saccular cerebral aneurysms that leave the parent artery intact.

AB - Background: Fusiform cerebral aneurysms are dilatations of the entire circumference of a segment of cerebral artery, usually considered due to atherosclerosis in adults. They are relatively thick-walled and elongated, causing neural compression or ischemia when discovered. We have noted a subset of fusiform cerebral aneurysms that vary from this common description. Patients: Out of a series of 472 intracranial aneurysms treated over 11 years, 11 patients between the ages 16 and 67 years (mean age 37) were identified who had discrete fusiform aneurysms unassociated with generalized cerebral atherosclerosis, connective tissue disorder or inflammation. Three presented with hemorrhage, six with neural compression by the aneurysm and two were discovered incidentally. Results: Nine aneurysms were located in the posterior circulation, the other two in the intracranial carotid artery. Their mean length and width were 16.3 and 11 mm, respectively. Three aneurysms contained thrombus. The eight aneurysms that were exposed surgically were partly or substantially thin-walled with normal appearing parent arteries. Eight were treated with proximal occlusion and three were circumferentially "wrapped". Parent artery occlusion caused one death and one mild disability and the remaining patients made good recoveries (follow-up 0.5-10 years). Conclusions: There is a subset of cerebral aneurysms with discrete fusiform morphology, apparently unrelated to cerebral atherosclerosis or systemic connective tissue disease, thin-walled in part or whole, more common in the vertebrobasilar system, and possessing a risk of rupture. Treatments currently available include proximal occlusion or aneurysm "wrapping", different approaches than neck-clipping or endovascular coiling of side-wall saccular cerebral aneurysms that leave the parent artery intact.

UR - http://www.scopus.com/inward/record.url?scp=0036197126&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036197126&partnerID=8YFLogxK

U2 - 10.1017/S0317167100001700

DO - 10.1017/S0317167100001700

M3 - Article

VL - 29

SP - 41

EP - 48

JO - Canadian Journal of Neurological Sciences

JF - Canadian Journal of Neurological Sciences

SN - 0317-1671

IS - 1

ER -