Nonhematological benefits of iron

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Iron deficiency anemia is common in people with chronic kidney disease (CKD) and its importance in supporting erythropoiesis is unquestioned especially in those patients treated with erythropoietin. Clinical symptomatology such as fatigability, cold intolerance, failure to concentrate and poor effort intolerance is often attributed to anemia or uremia. That iron deficiency, per se, can cause these symptoms is poorly recognized. Clinical and animal studies that support the benefits of iron supplementation, independent of increasing hemoglobin, such as those on immune function, physical performance, thermoregulation, cognition, and restless leg syndrome and aluminum absorption is the subject of this narrative review.

Original languageEnglish
Pages (from-to)565-571
Number of pages7
JournalAmerican Journal of Nephrology
Volume27
Issue number6
DOIs
StatePublished - Oct 2007

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Iron
Restless Legs Syndrome
Iron-Deficiency Anemias
Body Temperature Regulation
Erythropoiesis
Uremia
Erythropoietin
Aluminum
Chronic Renal Insufficiency
Cognition
Anemia
Hemoglobins
Clinical Studies

Keywords

  • Anemia
  • Chronic kidney disease
  • Cognitive function
  • Iron deficiency
  • Physical performance
  • Quality of life
  • Thermoregulation

ASJC Scopus subject areas

  • Nephrology

Cite this

Nonhematological benefits of iron. / Agarwal, Rajiv.

In: American Journal of Nephrology, Vol. 27, No. 6, 10.2007, p. 565-571.

Research output: Contribution to journalArticle

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