Noninvasive determination of total respiratory system compliance in infants by the weighted-spirometer method

Robert Tepper, R. D. Pagtakhan, L. M. Taussig

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

The weighted-spirometer method for noninvasive determination of static total respiratory system compliance (Crs) was adapted for use in infants. Ten normal newborns and 5 infants with bronchopulmonary dysplasia (BPD) were studied. The newborns had a mean Crs of 3.8 ml/cm H2O. Their mean specific Crs was 1.13 ml/cm H2O/kg body weight and 0.075 ml/cm H2O/cm body length. These Crs values were similar to those reported by other investigators who used the Hering-Breuer airway occlusion technique. The infants with BPD, who were of the same weight, height, and postconception age as the normal newborns, had significantly (p <0.05) lower mean specific Crs (0.60 ml/cm H2O/kg body weight and 0.047 ml/cm H2O/cm body length) relative to the normal newborns. These data suggest that intrinsic changes in lung elastic characteristics may contribute to the reduced lung compliance of infants with BPD. The weighted-spirometer method for measuring Crs is a potential tool for the noninvasive study of the elastic properties of the respiratory system during infancy in health and disease.

Original languageEnglish (US)
Pages (from-to)461-466
Number of pages6
JournalAmerican Review of Respiratory Disease
Volume130
Issue number3
StatePublished - 1984
Externally publishedYes

Fingerprint

Respiratory System
Bronchopulmonary Dysplasia
Compliance
Newborn Infant
Body Weight
Lung Compliance
Research Personnel
Weights and Measures
Lung
Health

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Noninvasive determination of total respiratory system compliance in infants by the weighted-spirometer method. / Tepper, Robert; Pagtakhan, R. D.; Taussig, L. M.

In: American Review of Respiratory Disease, Vol. 130, No. 3, 1984, p. 461-466.

Research output: Contribution to journalArticle

@article{16061ba89e804e0c932e540b161465e3,
title = "Noninvasive determination of total respiratory system compliance in infants by the weighted-spirometer method",
abstract = "The weighted-spirometer method for noninvasive determination of static total respiratory system compliance (Crs) was adapted for use in infants. Ten normal newborns and 5 infants with bronchopulmonary dysplasia (BPD) were studied. The newborns had a mean Crs of 3.8 ml/cm H2O. Their mean specific Crs was 1.13 ml/cm H2O/kg body weight and 0.075 ml/cm H2O/cm body length. These Crs values were similar to those reported by other investigators who used the Hering-Breuer airway occlusion technique. The infants with BPD, who were of the same weight, height, and postconception age as the normal newborns, had significantly (p <0.05) lower mean specific Crs (0.60 ml/cm H2O/kg body weight and 0.047 ml/cm H2O/cm body length) relative to the normal newborns. These data suggest that intrinsic changes in lung elastic characteristics may contribute to the reduced lung compliance of infants with BPD. The weighted-spirometer method for measuring Crs is a potential tool for the noninvasive study of the elastic properties of the respiratory system during infancy in health and disease.",
author = "Robert Tepper and Pagtakhan, {R. D.} and Taussig, {L. M.}",
year = "1984",
language = "English (US)",
volume = "130",
pages = "461--466",
journal = "American Journal of Respiratory and Critical Care Medicine",
issn = "1073-449X",
publisher = "American Thoracic Society",
number = "3",

}

TY - JOUR

T1 - Noninvasive determination of total respiratory system compliance in infants by the weighted-spirometer method

AU - Tepper, Robert

AU - Pagtakhan, R. D.

AU - Taussig, L. M.

PY - 1984

Y1 - 1984

N2 - The weighted-spirometer method for noninvasive determination of static total respiratory system compliance (Crs) was adapted for use in infants. Ten normal newborns and 5 infants with bronchopulmonary dysplasia (BPD) were studied. The newborns had a mean Crs of 3.8 ml/cm H2O. Their mean specific Crs was 1.13 ml/cm H2O/kg body weight and 0.075 ml/cm H2O/cm body length. These Crs values were similar to those reported by other investigators who used the Hering-Breuer airway occlusion technique. The infants with BPD, who were of the same weight, height, and postconception age as the normal newborns, had significantly (p <0.05) lower mean specific Crs (0.60 ml/cm H2O/kg body weight and 0.047 ml/cm H2O/cm body length) relative to the normal newborns. These data suggest that intrinsic changes in lung elastic characteristics may contribute to the reduced lung compliance of infants with BPD. The weighted-spirometer method for measuring Crs is a potential tool for the noninvasive study of the elastic properties of the respiratory system during infancy in health and disease.

AB - The weighted-spirometer method for noninvasive determination of static total respiratory system compliance (Crs) was adapted for use in infants. Ten normal newborns and 5 infants with bronchopulmonary dysplasia (BPD) were studied. The newborns had a mean Crs of 3.8 ml/cm H2O. Their mean specific Crs was 1.13 ml/cm H2O/kg body weight and 0.075 ml/cm H2O/cm body length. These Crs values were similar to those reported by other investigators who used the Hering-Breuer airway occlusion technique. The infants with BPD, who were of the same weight, height, and postconception age as the normal newborns, had significantly (p <0.05) lower mean specific Crs (0.60 ml/cm H2O/kg body weight and 0.047 ml/cm H2O/cm body length) relative to the normal newborns. These data suggest that intrinsic changes in lung elastic characteristics may contribute to the reduced lung compliance of infants with BPD. The weighted-spirometer method for measuring Crs is a potential tool for the noninvasive study of the elastic properties of the respiratory system during infancy in health and disease.

UR - http://www.scopus.com/inward/record.url?scp=0021184260&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021184260&partnerID=8YFLogxK

M3 - Article

C2 - 6383155

AN - SCOPUS:0021184260

VL - 130

SP - 461

EP - 466

JO - American Journal of Respiratory and Critical Care Medicine

JF - American Journal of Respiratory and Critical Care Medicine

SN - 1073-449X

IS - 3

ER -