Noninvasive surgery of prostate tissue by high intensity focused ultrasound: An updated report

N. T. Sanghvi, J. Syrus, R. S. Foster, R. Bihrle, R. Casey, T. Uchida

Research output: Contribution to journalConference article

2 Scopus citations

Abstract

High Intensity Focused Ultrasound (HIFU) has been clinically used for the treatment of benign prostatic hyperplasia (BPH) and it is experimentally applied for the treatment of localized prostate cancer (PC). Recent advances in the transducer material and technology have permitted to combine the ultrasound visualization capability and HIFU on the same ceramic crystal. Also, the transducer efficiency has increased to a level that a smaller size intracavity probe can be made to produce sufficient acoustic power required for the focused ultrasound surgery of the prostate. Using this technology, 4 MHz mechanically scanning transrectal ultrasound probes has been designed. The transrectal probes are used with Sonablate (SB-200, manufactured by Focus Surgery, Inc., Indianapolis, IN) device. The SB-200 produces both transverse and longitudinal images of the prostate. The transverse and longitudinal images are used for selection of tissue volume, treatment planning and monitoring of tissue during the HIFU treatment cycle. The paper reviews the present operation of the device and recent clinical protocol that has improved efficiency, efficacy and safety of the device. The two years follow-up clinical results from the multi-site US Pilot Study (USPS) and The Male Health Centre are compared with the Kitasato-study (Kitasato School of Medicine, Sagamihara, Japan).

Original languageEnglish (US)
Pages (from-to)194-200
Number of pages7
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3907
StatePublished - Jan 1 2000
EventLasers in Surgery: Advanced Characterization, Therapeutics, and Systems X - San Jose, CA, USA
Duration: Jan 22 2000Jan 25 2000

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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