Potassium is capable of producing in the dog nonparoxysmal A-V nodal tachycardia. The paradox of depression of A-V conduction and simultaneous increase of automaticity may be explained on the basis of functional differentiation within the A-V conduction system. The failure of potassium to significantly affect the pacemaker and conducting tissue in the isolated heart, its failure to produce non-paroxysmal A-V nodal tachycardia in man and the similarity of the arrhythmia observed in our experiments with that induced by digitalis in human subjects were stressed.
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine