Normative data for neuropsychological tests in a rural elderly chinese cohort

Lili Yang, Frederick W. Unverzagt, Yinlong Jin, Hugh C. Hendrie, Chaoke Liang, Kathleen S. Hall, Jingxiang Cao, Feng Ma, Jill R. Murrell, Yibin Cheng, Ping Li, Jianchao Bian, Sujuan Gao

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Normative information is important for appropriate interpretation of cognitive test scores as a critical component of dementia diagnosis in the elderly population. A cross-sectional evaluation of 1826 participants aged 65 years and older from four rural counties in China was conducted using six cognitive instruments including tests of global cognitive function (the Community Screening Instrument for Dementia), memory (Word List Learning and Recall tasks from the Consortium to Establish a Registry for Alzheimer's Disease, IU Story), language (Animal Fluency Test), and executive function (IU Token). Multiple regression models adjusting for demographic variables were used to provide standardized residuals z-scores and corresponding percentile ranking for each cognitive test. In all cognitive tests older age was associated with worse test performance while exposure to education was related to better cognitive test performance. We also detected a significant gender difference with men scoring better than women and a significant gender by education interaction on two tests. The interaction indicates that gender difference in test scores was much smaller in participants with more education than those who had less or no education. These demographically adjusted, regression-based norms can be a useful tool to clinicians involved with differential diagnosis of cognitive and memory disorders in older adults in rural China.

Original languageEnglish (US)
Pages (from-to)641-653
Number of pages13
JournalClinical Neuropsychologist
Volume26
Issue number4
DOIs
StatePublished - May 1 2012

Fingerprint

Neuropsychological Tests
Education
Dementia
China
Executive Function
Memory Disorders
Cognition
Registries
Alzheimer Disease
Differential Diagnosis
Language
Demography
Learning
Cohort
Population

Keywords

  • Age
  • Education
  • Gender
  • Neuropsychological test
  • Normative study
  • Regression-based norms

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Arts and Humanities (miscellaneous)
  • Developmental and Educational Psychology
  • Medicine(all)

Cite this

Normative data for neuropsychological tests in a rural elderly chinese cohort. / Yang, Lili; Unverzagt, Frederick W.; Jin, Yinlong; Hendrie, Hugh C.; Liang, Chaoke; Hall, Kathleen S.; Cao, Jingxiang; Ma, Feng; Murrell, Jill R.; Cheng, Yibin; Li, Ping; Bian, Jianchao; Gao, Sujuan.

In: Clinical Neuropsychologist, Vol. 26, No. 4, 01.05.2012, p. 641-653.

Research output: Contribution to journalArticle

Yang, Lili ; Unverzagt, Frederick W. ; Jin, Yinlong ; Hendrie, Hugh C. ; Liang, Chaoke ; Hall, Kathleen S. ; Cao, Jingxiang ; Ma, Feng ; Murrell, Jill R. ; Cheng, Yibin ; Li, Ping ; Bian, Jianchao ; Gao, Sujuan. / Normative data for neuropsychological tests in a rural elderly chinese cohort. In: Clinical Neuropsychologist. 2012 ; Vol. 26, No. 4. pp. 641-653.
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