Oat cell carcinoma of the lung. Early treatment results of combination radiation therapy and chemotherapy

N. B. Hornback, Lawrence Einhorn, H. Shidnia, B. T. Joe, M. Krause, B. Furnas

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Since August 1974, 50 patients with histologically proven oat cell carcinoma of the lung were treated at Indiana University Hospitals with a combination of adriamycin, cyclophosphamide, Oncovin, BCG immunotherapy, and radiation therapy to the primary lung tumor and whole brain. Twenty nine patients are eligible for a 6 month follow up and are included in this report. All 29 patients responded to therapy; 12 patients (41%) had a minimum of 50% reduction in tumor mass and 17 patients (59%) had complete clinical remission of disease. Eight (38%) of the 29 patients have remained in complete remission from 6 to 14 months, and 90% of the patients survived a minimum of 6 months. This represents a considerable improvement in survival rates over what had been obtained at Indiana University Hospitals previously.

Original languageEnglish
Pages (from-to)2658-2664
Number of pages7
JournalCancer
Volume37
Issue number6
DOIs
StatePublished - 1976

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Small Cell Lung Carcinoma
Radiotherapy
Drug Therapy
Therapeutics
Vincristine
Mycobacterium bovis
Brain Neoplasms
Immunotherapy
Doxorubicin
Cyclophosphamide
Survival Rate
Lung
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Oat cell carcinoma of the lung. Early treatment results of combination radiation therapy and chemotherapy. / Hornback, N. B.; Einhorn, Lawrence; Shidnia, H.; Joe, B. T.; Krause, M.; Furnas, B.

In: Cancer, Vol. 37, No. 6, 1976, p. 2658-2664.

Research output: Contribution to journalArticle

Hornback, N. B. ; Einhorn, Lawrence ; Shidnia, H. ; Joe, B. T. ; Krause, M. ; Furnas, B. / Oat cell carcinoma of the lung. Early treatment results of combination radiation therapy and chemotherapy. In: Cancer. 1976 ; Vol. 37, No. 6. pp. 2658-2664.
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