Obese children with steatohepatitis can develop cirrhosis in childhood

Jean Molleston, Frances White, Jeffrey Teckman, Joseph F. Fitzgerald

Research output: Contribution to journalArticle

178 Citations (Scopus)

Abstract

Nonalcoholic steatohepatitis, in which fatty change and inflammation of the liver occur in the absence of excess alcohol intake, is increasingly recognized in obese children. Although fibrosis is common in pediatric nonalcoholic steatohepatitis, cirrhosis has been reported rarely. The two boys reported here developed cirrhosis from nonalcoholic steatohepatitis at ages 10 and 14 yr. One child progressed to cirrhosis with symptomatic portal hypertension within a 2-yr period.

Original languageEnglish
Pages (from-to)2460-2462
Number of pages3
JournalAmerican Journal of Gastroenterology
Volume97
Issue number9
DOIs
StatePublished - Sep 2002

Fingerprint

Fatty Liver
Fibrosis
Portal Hypertension
Alcohols
Pediatrics
Inflammation
Liver
Non-alcoholic Fatty Liver Disease

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Obese children with steatohepatitis can develop cirrhosis in childhood. / Molleston, Jean; White, Frances; Teckman, Jeffrey; Fitzgerald, Joseph F.

In: American Journal of Gastroenterology, Vol. 97, No. 9, 09.2002, p. 2460-2462.

Research output: Contribution to journalArticle

Molleston, Jean ; White, Frances ; Teckman, Jeffrey ; Fitzgerald, Joseph F. / Obese children with steatohepatitis can develop cirrhosis in childhood. In: American Journal of Gastroenterology. 2002 ; Vol. 97, No. 9. pp. 2460-2462.
@article{7ad6c18cc6114203811d51c8e0d05489,
title = "Obese children with steatohepatitis can develop cirrhosis in childhood",
abstract = "Nonalcoholic steatohepatitis, in which fatty change and inflammation of the liver occur in the absence of excess alcohol intake, is increasingly recognized in obese children. Although fibrosis is common in pediatric nonalcoholic steatohepatitis, cirrhosis has been reported rarely. The two boys reported here developed cirrhosis from nonalcoholic steatohepatitis at ages 10 and 14 yr. One child progressed to cirrhosis with symptomatic portal hypertension within a 2-yr period.",
author = "Jean Molleston and Frances White and Jeffrey Teckman and Fitzgerald, {Joseph F.}",
year = "2002",
month = "9",
doi = "10.1016/S0002-9270(02)04360-5",
language = "English",
volume = "97",
pages = "2460--2462",
journal = "American Journal of Gastroenterology",
issn = "0002-9270",
publisher = "Nature Publishing Group",
number = "9",

}

TY - JOUR

T1 - Obese children with steatohepatitis can develop cirrhosis in childhood

AU - Molleston, Jean

AU - White, Frances

AU - Teckman, Jeffrey

AU - Fitzgerald, Joseph F.

PY - 2002/9

Y1 - 2002/9

N2 - Nonalcoholic steatohepatitis, in which fatty change and inflammation of the liver occur in the absence of excess alcohol intake, is increasingly recognized in obese children. Although fibrosis is common in pediatric nonalcoholic steatohepatitis, cirrhosis has been reported rarely. The two boys reported here developed cirrhosis from nonalcoholic steatohepatitis at ages 10 and 14 yr. One child progressed to cirrhosis with symptomatic portal hypertension within a 2-yr period.

AB - Nonalcoholic steatohepatitis, in which fatty change and inflammation of the liver occur in the absence of excess alcohol intake, is increasingly recognized in obese children. Although fibrosis is common in pediatric nonalcoholic steatohepatitis, cirrhosis has been reported rarely. The two boys reported here developed cirrhosis from nonalcoholic steatohepatitis at ages 10 and 14 yr. One child progressed to cirrhosis with symptomatic portal hypertension within a 2-yr period.

UR - http://www.scopus.com/inward/record.url?scp=0036735880&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036735880&partnerID=8YFLogxK

U2 - 10.1016/S0002-9270(02)04360-5

DO - 10.1016/S0002-9270(02)04360-5

M3 - Article

C2 - 12358273

AN - SCOPUS:0036735880

VL - 97

SP - 2460

EP - 2462

JO - American Journal of Gastroenterology

JF - American Journal of Gastroenterology

SN - 0002-9270

IS - 9

ER -