Odontoblast morphology and dental repair

P. E. Murray, I. About, P. J. Lumley, J. C. Franquin, L. Windsor, A. J. Smith

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objectives. To investigate the changes in morphology and activity of pulp odontoblasts in response to cavity restoration variables and patient factors. Methods. Class V non exposed cavities were prepared in the intact 1st or 2nd premolar teeth of 27 patients, aged between 9 and 17 years-old. Following tooth extraction, the area of reactionary dentine and the area of the odontoblasts were measured using computerised histomorphometry. Results. The cytoplasm to nucleus ratio of the odontoblasts was found to increase beneath cut dentinal tubules, following the secretion of reactionary dentine. However, none of the patient or preparation variables were found to be correlated with changes in the odontoblast cytoplasm to nucleus ratio. Conclusions. Morphological changes in human odontoblasts is directly related to their capacity to repair dentine injuries and provide pulp protection. Changes in odontoblast morphology reflect secretory activity.

Original languageEnglish (US)
Pages (from-to)75-82
Number of pages8
JournalJournal of Dentistry
Volume31
Issue number1
DOIs
StatePublished - Jan 1 2003

Fingerprint

Odontoblasts
Tooth
Dentin
Cytoplasm
Tooth Extraction
Bicuspid
Wounds and Injuries

Keywords

  • Cavity restoration
  • Odontoblast
  • Pulp
  • Tertiary dentinogenesis

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Murray, P. E., About, I., Lumley, P. J., Franquin, J. C., Windsor, L., & Smith, A. J. (2003). Odontoblast morphology and dental repair. Journal of Dentistry, 31(1), 75-82. https://doi.org/10.1016/S0300-5712(02)00089-1

Odontoblast morphology and dental repair. / Murray, P. E.; About, I.; Lumley, P. J.; Franquin, J. C.; Windsor, L.; Smith, A. J.

In: Journal of Dentistry, Vol. 31, No. 1, 01.01.2003, p. 75-82.

Research output: Contribution to journalArticle

Murray, PE, About, I, Lumley, PJ, Franquin, JC, Windsor, L & Smith, AJ 2003, 'Odontoblast morphology and dental repair', Journal of Dentistry, vol. 31, no. 1, pp. 75-82. https://doi.org/10.1016/S0300-5712(02)00089-1
Murray PE, About I, Lumley PJ, Franquin JC, Windsor L, Smith AJ. Odontoblast morphology and dental repair. Journal of Dentistry. 2003 Jan 1;31(1):75-82. https://doi.org/10.1016/S0300-5712(02)00089-1
Murray, P. E. ; About, I. ; Lumley, P. J. ; Franquin, J. C. ; Windsor, L. ; Smith, A. J. / Odontoblast morphology and dental repair. In: Journal of Dentistry. 2003 ; Vol. 31, No. 1. pp. 75-82.
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