Ofloxacin versus doxycycline for treatment of cervical infection with Chlamydia trachomatis

T. M. Hooton, Byron Batteiger, F. N. Judson, S. L. Spruance, W. E. Stamm

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Women with culture-proven Chlamydia trachomatis cervical infection were randomized to receive either ofloxacin (300 mg) or doxycycline (100 mg), orally twice daily for 7 days. All 56 had negative cultures 5 to 9 days after treatment. Four weeks after treatment, 26 (93%) of 28 ofloxacin-treated patients and all 22 doxycycline-treated patients were cured. We conclude that 300 mg of ofloxacin given twice daily for 7 days provides effective therapy for chlamydial infection of the cervix.

Original languageEnglish (US)
Pages (from-to)1144-1146
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume36
Issue number5
StatePublished - 1992
Externally publishedYes

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Ofloxacin
Doxycycline
Chlamydia trachomatis
Infection
Cervix Uteri
Therapeutics

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Ofloxacin versus doxycycline for treatment of cervical infection with Chlamydia trachomatis. / Hooton, T. M.; Batteiger, Byron; Judson, F. N.; Spruance, S. L.; Stamm, W. E.

In: Antimicrobial Agents and Chemotherapy, Vol. 36, No. 5, 1992, p. 1144-1146.

Research output: Contribution to journalArticle

Hooton, T. M. ; Batteiger, Byron ; Judson, F. N. ; Spruance, S. L. ; Stamm, W. E. / Ofloxacin versus doxycycline for treatment of cervical infection with Chlamydia trachomatis. In: Antimicrobial Agents and Chemotherapy. 1992 ; Vol. 36, No. 5. pp. 1144-1146.
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