Ofloxacin versus doxycycline for treatment of cervical infection with Chlamydia trachomatis

T. M. Hooton, B. E. Batteiger, F. N. Judson, S. L. Spruance, W. E. Stamm

Research output: Contribution to journalComment/debate

34 Scopus citations


Women with culture-proven Chlamydia trachomatis cervical infection were randomized to receive either ofloxacin (300 mg) or doxycycline (100 mg), orally twice daily for 7 days. All 56 had negative cultures 5 to 9 days after treatment. Four weeks after treatment, 26 (93%) of 28 ofloxacin-treated patients and all 22 doxycycline-treated patients were cured. We conclude that 300 mg of ofloxacin given twice daily for 7 days provides effective therapy for chlamydial infection of the cervix.

Original languageEnglish (US)
Pages (from-to)1144-1146
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Issue number5
StatePublished - Jan 1 1992


ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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