Old dog PU.1 reveals new tricks

Research output: Contribution to journalArticle

Abstract

The transcription factor PU.1 is not needed for the maintenance of neutrophil identity but is essential for the prevention of excessive tissue damage due to a prolonged immune response. PU.1 restrains the activation of neutrophils by antagonizing the AP-1 transcription factor JunB.

Original languageEnglish (US)
Pages (from-to)520-522
Number of pages3
JournalNature Immunology
Volume20
Issue number5
DOIs
StatePublished - May 1 2019

Fingerprint

Neutrophil Activation
Transcription Factor AP-1
Neutrophils
Maintenance
Dogs
proto-oncogene protein Spi-1

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Old dog PU.1 reveals new tricks. / Dahl, Richard.

In: Nature Immunology, Vol. 20, No. 5, 01.05.2019, p. 520-522.

Research output: Contribution to journalArticle

Dahl, Richard. / Old dog PU.1 reveals new tricks. In: Nature Immunology. 2019 ; Vol. 20, No. 5. pp. 520-522.
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