Old dog PU.1 reveals new tricks

Research output: Contribution to journalArticlepeer-review

Abstract

The transcription factor PU.1 is not needed for the maintenance of neutrophil identity but is essential for the prevention of excessive tissue damage due to a prolonged immune response. PU.1 restrains the activation of neutrophils by antagonizing the AP-1 transcription factor JunB.

Original languageEnglish (US)
Pages (from-to)520-522
Number of pages3
JournalNature Immunology
Volume20
Issue number5
DOIs
StatePublished - May 1 2019
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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