Oncocytoma-like angiomyolipoma: A clinicopathologic and immunohistochemical study of 2 cases

Guido Martignoni, Maurizio Pea, Franco Bonetti, Matteo Brunelli, John Eble

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

We report the clinical, pathologic, and immunohistochemical features of an unusual tumor of the kidney composed of densely eosinophilic, polygonal epithelioid cells. The patients were a 56-year-old woman and a 35-year-old man. The renal tumors were discovered during follow-up for breast carcinoma and evaluation for abdominal pain, respectively. The tumors closely resembled oncocytoma in routine sections, but were negative for epithelial markers and positive for HMB-45, a pattern of reactions characteristic of angiomyolipoma. In the woman, a single additional microscopic angiomyolipoma was present in the renal parenchyma at a distance from the main tumor. Both patients are alive without recurrence 7 and 10 years after surgery, respectively. Based on clinical, morphologic, and immunophenotypic features, we conclude that these tumors are oncocytoma-like angiomyolipomas.

Original languageEnglish (US)
Pages (from-to)610-612
Number of pages3
JournalArchives of Pathology and Laboratory Medicine
Volume126
Issue number5
StatePublished - 2002
Externally publishedYes

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Oxyphilic Adenoma
Angiomyolipoma
Neoplasms
Kidney
Epithelioid Cells
Abdominal Pain
Breast Neoplasms
Recurrence

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Oncocytoma-like angiomyolipoma : A clinicopathologic and immunohistochemical study of 2 cases. / Martignoni, Guido; Pea, Maurizio; Bonetti, Franco; Brunelli, Matteo; Eble, John.

In: Archives of Pathology and Laboratory Medicine, Vol. 126, No. 5, 2002, p. 610-612.

Research output: Contribution to journalArticle

Martignoni, Guido ; Pea, Maurizio ; Bonetti, Franco ; Brunelli, Matteo ; Eble, John. / Oncocytoma-like angiomyolipoma : A clinicopathologic and immunohistochemical study of 2 cases. In: Archives of Pathology and Laboratory Medicine. 2002 ; Vol. 126, No. 5. pp. 610-612.
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