One-Year Follow-Up of Girls with Precocious Puberty and Their Mothers: Do Psychological Assessments Change over Time or with Treatment?

Melissa J. Schoelwer, Kelly L. Donahue, Paula Didrick, Erica Eugster

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: To determine whether psychological characteristics of girls with variations of early puberty and their mothers change over time and with treatment in girls with central precocious puberty (CPP). Methods: Girls with CPP, premature adrenarche (PA), and early normal puberty (ENP) completed psychological assessments at baseline and after 1 year along with their mothers. All girls with CPP were treated with GnRH analogs. Psychological effects of group and time were examined using 2 × 3 mixed ANOVAs. Results: Sixty-two subjects aged 7.5 ± 1.4 years (range 4.8–10.5) were enrolled, of whom 36 (15 with CPP, 8 with PA, and 13 with ENP) completed 1-year follow-up assessments. Psychological measures were normal in all girls. No significant group differences were found for any measure of girls’ psychological functioning at either time point. However, across all groups there was change over time with a decrease in perceived physical competence (p < 0.001) and an increase in perceived maternal acceptance (p = 0.001). Conclusion: No abnormalities in psychological functioning were found among girls with variations of early puberty, and all groups were in the normal range. Our results are largely reassuring regarding concerns of adverse psychological consequences of early puberty in girls.

Original languageEnglish (US)
JournalHormone Research in Paediatrics
DOIs
StateAccepted/In press - Sep 19 2017

Fingerprint

Precocious Puberty
Mothers
Psychology
Puberty
Adrenarche
Therapeutics
Gonadotropin-Releasing Hormone
Mental Competency
Analysis of Variance
Reference Values
Central Precocious Puberty

Keywords

  • Central precocious puberty
  • GnRH analog
  • Premature adrenarche
  • Psychopathology

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

One-Year Follow-Up of Girls with Precocious Puberty and Their Mothers : Do Psychological Assessments Change over Time or with Treatment? / Schoelwer, Melissa J.; Donahue, Kelly L.; Didrick, Paula; Eugster, Erica.

In: Hormone Research in Paediatrics, 19.09.2017.

Research output: Contribution to journalArticle

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