Optical recording-guided pacing to create functional line of block during ventricular fibrillation

Krishna Ravi, Motoki Nihei, Anjuli Willmer, Hideki Hayashi, Shien-Fong Lin

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Low-energy defibrillation is very desirable in cardiac rhythm management. We previously reported that ventricular fibrillation (VF) can be synchronized with a novel synchronized pacing technique (SyncP) using low-energy pacing pulses. This study sought to create a line of block during VF using SyncP. SyncP was performed in six isolated rabbit hearts during VF using optical recording to control the delivery of pacing pulses in real time. Four pacing electrodes with interelectrode distances of 5 mm were configured in a line along and across the myocardial fiber direction. The electrodes were controlled independently (independent mode) or fired together (simultaneous mode). Significant wavefront synchronization was observed along the electrode line as indicated by a decrease in variance. With the independent SyncP protocol, the decrease in the variance was 19.3 and 13.7% (P

Original languageEnglish (US)
Article number021013
JournalJournal of Biomedical Optics
Volume11
Issue number2
DOIs
StatePublished - Mar 2006
Externally publishedYes

Fingerprint

fibrillation
Optical recording
Ventricular Fibrillation
Electrodes
recording
Cardiac rhythm management
electrodes
rhythm
rabbits
Wavefronts
pulses
synchronism
delivery
Synchronization
Rabbits
fibers
energy
Fibers

Keywords

  • Defibrillation
  • Optical mapping
  • Pacing
  • Ventricular fibrillation

ASJC Scopus subject areas

  • Biomedical Engineering
  • Biomaterials
  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Clinical Biochemistry

Cite this

Optical recording-guided pacing to create functional line of block during ventricular fibrillation. / Ravi, Krishna; Nihei, Motoki; Willmer, Anjuli; Hayashi, Hideki; Lin, Shien-Fong.

In: Journal of Biomedical Optics, Vol. 11, No. 2, 021013, 03.2006.

Research output: Contribution to journalArticle

Ravi, Krishna ; Nihei, Motoki ; Willmer, Anjuli ; Hayashi, Hideki ; Lin, Shien-Fong. / Optical recording-guided pacing to create functional line of block during ventricular fibrillation. In: Journal of Biomedical Optics. 2006 ; Vol. 11, No. 2.
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